Results 111 to 120 of about 168,520 (319)
Molecular mechanisms in haematological malignancies [PDF]
, 2009 Haematopoiesis requires the constant production of large numbers of peripheral blood cells. This process is under tight control of transcription factor networks as well as cytokines, growth factors and hormones.
Avellino, Roberto +2 more
core
Cloning and expression of codon-optimized recombinant darbepoetin alfa in Leishmania tarentolae T7-TR [PDF]
, 2016 Darbepoetin alfa is an engineered and hyperglycosylated analog of recombinant human erythropoietin (EPO) which is used as a drug in treating anemia in patients with chronic kidney failure and cancer.
Fard-Esfahani, P. +8 more
core +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
Allergy, EarlyView.ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Neuroprotective effect of erythropoietin on anesthesia-induced neurotoxicity through the modulation of autophagy in [PDF]
Korean Journal of AnesthesiologyBackground The anti-oxidative, anti-inflammatory, and anti-apoptotic effects of erythropoietin may provide neuroprotective effects. Erythropoietin also modulates autophagy signaling that may play a role in anesthesia-induced neurotoxicity (AIN).
Bon-Wook Koo +5 more
doaj +1 more source
Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate
Journal of Experimental Medicine, 2014 Erythropoietin suppresses non-erythroid cell fate options to induce an erythroid lineage bias at all lineage bifurcations between HSCs and committed erythroid progenitors.
A. Grover +8 more
semanticscholar +1 more source
The role of iron in normal and impaired testicular function
Andrology, EarlyView.Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
Turkish Journal of Nephrology, 2019 The correction of anemia in hemodialysis patients with erythropoietin increases appetite, anabolic effects, and improves physical, psychologyical activities and endocrine functions.
Kuddusi CENGİZ +3 more
doaj
Testosterone Versus Clomiphene Treatment of Hypogonadism: A Retrospective Analysis in US Veterans
Andrology, EarlyView.ABSTRACT Background Male hypogonadotropic hypogonadism is a complex condition with a multifactorial etiology. Although testosterone replacement therapy (TRT) is the only approved treatment for male hypogonadism, clomiphene citrate (CC) is often used as an off‐label treatment.
Shourya Tadisina +6 more
wiley +1 more source
Serum Erythropoietin level in children with different degrees of chronic renal failure
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2000 Objective: Kidneys are major sites of erythropoietin production and in chronic renal failure (CRF), erythropoietin production decreases and leads to anemia. This study was done in children with different degrees of CRF and with primary disease of tubules
Gh Al-Hosseini Hashemi +2 more
doaj
Биопрепараты: Профилактика, диагностика, лечение, 2018 The method for the assessment of biological activity of erythropoietin preparations in vitro on TF-1 sensitive cells culture has been developed. The special characteristics of measurements and calculations of the biological activity of erythropoietin ...
N. A. Gavrilova +3 more
doaj