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Veterinary Clinics of North America: Small Animal Practice, 2003
EPO is a hematopoietic growth factor produced in the kidney that stimulates erythropoiesis. It effectively treats hypoproliferative anemia associated with CRF, improving quality of life in these patients. Other uses that are poorly characterized in veterinary medicine include treatment of cancer patients on chemotherapy, hematologic disorders, and ...
Nyssa J. Reine +2 more
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EPO is a hematopoietic growth factor produced in the kidney that stimulates erythropoiesis. It effectively treats hypoproliferative anemia associated with CRF, improving quality of life in these patients. Other uses that are poorly characterized in veterinary medicine include treatment of cancer patients on chemotherapy, hematologic disorders, and ...
Nyssa J. Reine +2 more
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Erythropoietin pathophysiology and erythropoietin deficiency anemia
The Hematology Journal, 2004Review aerticle on erythropoietin pathophysiology and erythropoietin deficiency anemia.
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The International Journal of Biochemistry & Cell Biology, 1999
The erythropoietin (epo) receptor is a member of the cytokine receptor family. It is expressed almost exclusively on erythroid precursor cells and controls the development of red blood cells. The epo receptor has no intrinsic kinase activity, but binds intracellular tyrosine kinases to elicit its signals.
Peta A. Tilbrook, S. Peter Klinken
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The erythropoietin (epo) receptor is a member of the cytokine receptor family. It is expressed almost exclusively on erythroid precursor cells and controls the development of red blood cells. The epo receptor has no intrinsic kinase activity, but binds intracellular tyrosine kinases to elicit its signals.
Peta A. Tilbrook, S. Peter Klinken
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Seminars in Oncology, 2001
Erythropoietin (EPO) is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. The EPO receptor belongs to the same family of receptors as growth hormone, granulocyte-colony stimulating factor, granulocyte macrophage-colony stimulating factor, and some interleukins.
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Erythropoietin (EPO) is the primary regulator of erythropoiesis, and promotes the survival, proliferation, and differentiation of erythroid progenitor cells. The EPO receptor belongs to the same family of receptors as growth hormone, granulocyte-colony stimulating factor, granulocyte macrophage-colony stimulating factor, and some interleukins.
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2001
Hypoxia induces tissue-specific gene products such as erythropoietin (EPO) and vascular endothelial growth factor (VEGF), which improve the peripheral O2 supply, and glucose transporters and glycolytic enzymes, which adapt cells to reduced O2 availability. EPO has been the fountainhead in research on pO2-dependent synthesis of proteins.
Wolfgang Jelkmann +1 more
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Hypoxia induces tissue-specific gene products such as erythropoietin (EPO) and vascular endothelial growth factor (VEGF), which improve the peripheral O2 supply, and glucose transporters and glycolytic enzymes, which adapt cells to reduced O2 availability. EPO has been the fountainhead in research on pO2-dependent synthesis of proteins.
Wolfgang Jelkmann +1 more
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New England Journal of Medicine, 1971
Studies of the regulation of red-cell production have recently taken on some urgency because of the potential usefulness of erythropoietin in the treatment of patients with anemia due to chronic re...
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Studies of the regulation of red-cell production have recently taken on some urgency because of the potential usefulness of erythropoietin in the treatment of patients with anemia due to chronic re...
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New England Journal of Medicine, 2007
Dialysis facilities can make more money from administering epoetin than from dialysis and related routine services, which Medicare has reimbursed at a composite rate since 1983. Dr. Robert Steinbrook writes that in 2007, Congress may consider whether to eliminate financial incentives that may lead to the overuse of epoetin and other separately billable
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Dialysis facilities can make more money from administering epoetin than from dialysis and related routine services, which Medicare has reimbursed at a composite rate since 1983. Dr. Robert Steinbrook writes that in 2007, Congress may consider whether to eliminate financial incentives that may lead to the overuse of epoetin and other separately billable
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DMW - Deutsche Medizinische Wochenschrift, 2008
Jiuwei Cui, Yaacov Ben-David
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Jiuwei Cui, Yaacov Ben-David
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2009
Erythropoietin (EPO), a glycoprotein hormone, stimulates the growth of red blood cells and as a consequence it increases tissue oxygenation. This performance enhancing effect is responsible for the ban of erythropioetin in sports since 1990. Especially its recombinant synthesis led to the abuse of this hormone, predominatly in endurance sports.
Christian Reichel, Günter Gmeiner
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Erythropoietin (EPO), a glycoprotein hormone, stimulates the growth of red blood cells and as a consequence it increases tissue oxygenation. This performance enhancing effect is responsible for the ban of erythropioetin in sports since 1990. Especially its recombinant synthesis led to the abuse of this hormone, predominatly in endurance sports.
Christian Reichel, Günter Gmeiner
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2016
Epoetin is the primary and physiological regulator of erythropoiesis, i.e. the production of red blood cells. It is a glycoprotein produced predominantly in the fetal liver and the adult kidney, circulates into the adult bone marrow, and binds to its dimerizing receptor on the surface of erythroid progenitor cells to promote cell survival ...
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Epoetin is the primary and physiological regulator of erythropoiesis, i.e. the production of red blood cells. It is a glycoprotein produced predominantly in the fetal liver and the adult kidney, circulates into the adult bone marrow, and binds to its dimerizing receptor on the surface of erythroid progenitor cells to promote cell survival ...
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