Results 21 to 30 of about 91,559 (219)

Adverse clinical outcomes associated with infections by Enterobacterales producing ESBL (ESBL-E): a systematic review and meta-analysis.

JAC-Antimicrobial Resistance, 2021
Objectives Enterobacterales producing ESBL (ESBL-E) have been notable for their rapid expansion in community settings. This systematic review and meta-analysis aimed to summarize evidence investigating the association between ESBL-E infection and adverse
Weiping Ling, L. Furuya-Kanamori, Yukiko Ezure, P. Harris, D. Paterson   +4 more
semanticscholar   +1 more source

Phenotypic and Genotypic Profile of Enterobacteriaceae Isolated at a Teaching Hospital in Ghana. [PDF]

Microbiologyopen
This study identified a significant prevalence of antimicrobial resistance determinants within Enterobacteriaceae isolates, with particular emphasis on those producing extended‐spectrum β‐lactamases (ESBL). These isolates harbored diverse antibiotic resistance genes (ARGs), plasmid replicons, and virulence factors (VFs), highlighting the imperative for
Donkor B, Mills RO, Mwintige P, Moses AB, Brown AA, Halm-Lai F, Hagan OCK.   +6 more
europepmc   +2 more sources

Carbapenem-Sparing Strategies for ESBL Producers: When and How

Antibiotics, 2020
Extended spectrum β-lactamase (ESBL)-producing bacteria are prevalent worldwide and correlated with hospital infections, but they have been evolving as an increasing cause of community acquired infections.
I. Karaiskos, H. Giamarellou
semanticscholar   +1 more source

Plasmid- and strain-specific factors drive variation in ESBL-plasmid spread in vitro and in vivo

The ISME Journal, 2020
Horizontal gene transfer, mediated by conjugative plasmids, is a major driver of the global rise of antibiotic resistance. However, the relative contributions of factors that underlie the spread of plasmids and their roles in conjugation in vivo are ...
F. Benz, J. Huisman, Erik Bakkeren, Joana A. Herter, T. Stadler, M. Ackermann, Médéric Diard, A. Egli, A. Hall, W. Hardt, S. Bonhoeffer   +10 more
semanticscholar   +1 more source

Extended-Spectrum β-Lactamase (ESBL) Genotypes among Multidrug-Resistant Uropathogenic Escherichia coli Clinical Isolates from a Teaching Hospital of Nepal

Interdisciplinary Perspectives on Infectious Diseases, 2020
Urinary tract infections (UTI) represent the most common bacterial infections among patients visiting outpatient clinics of healthcare centers in Nepal.
R. Pandit, B. Awal, S. Shrestha, G. Joshi, B. Rijal, N. Parajuli   +5 more
semanticscholar   +1 more source

Treatment Failure in Urinary Tract Infections: A Warning Witness for Virulent Multi-Drug Resistant ESBL- Producing Escherichia coli

Infection and Drug Resistance, 2020
Background Global increase in the prevalence of virulent extended-spectrum beta-lactamase (ESBL)-producing uropathogenic Escherichia coli (UPEC), which is also multi-drug resistant (MDR), leads to increase in severity of urinary tract infections (UTIs ...
Z. Naziri, A. Derakhshandeh, A. Soltani Borchaloee, Meisam Poormaleknia, Negar Azimzadeh   +4 more
semanticscholar   +1 more source

Detection and Characterization of ESBL-Producing Escherichia coli From Humans and Poultry in Ghana

Frontiers in Microbiology, 2019
Introduction: The increasing incidence of infections caused by extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli in sub-Saharan Africa is of serious concern.
L. Falgenhauer, C. Imirzalioglu, K. Oppong, Charity Wiafe Akenten, B. Hogan, R. Krumkamp, S. Poppert, Vinzent Levermann, Oliver Schwengers, N. Sarpong, E. Owusu-Dabo, J. May, D. Eibach   +12 more
semanticscholar   +1 more source

Prevalence of extended-spectrum β-lactamase (ESBL) and molecular detection of blaTEM, blaSHV and blaCTX-M genotypes among Enterobacteriaceae isolates from patients in Khartoum, Sudan

The Pan African Medical Journal, 2020
Introduction the emergence of antibiotic resistance pathogens is an important health risk. Usually Gram negative bacteria acquire resistance to beta-lactam antibiotics by beta-lactamase production.
M. Dirar, N. Bilal, M. Ibrahim, M. Hamid
semanticscholar   +1 more source

Distribution of quinolone resistance gene (qnr) in ESBL-producing Escherichia coli and Klebsiella spp. in Lomé, Togo

Antimicrobial Resistance and Infection Control, 2019
Qnr genes are known to confer a low-level resistance to fluoroquinolone in Enterobacteriaceae. They are often found on the same resistance plasmids as extended spectrum β-lactamase (ESBL) and constitute the most common antibiotic resistance mechanism ...
F. Salah, S. Soubeiga, A. Ouattara, A. Sadji, A. Metuor-Dabiré, D. Obiri-Yeboah, Abiba Banla-Kere, S. Karou, J. Simporé   +8 more
semanticscholar   +1 more source

Extended Spectrum β-Lactamase (ESBL) Producing Escherichia coli in Pigs and Pork Meat in the European Union

Antibiotics, 2020
The aim of this article is to review the fast and worldwide distribution of ESBL enzymes and to describe the role of the pork production chain as a reservoir and transmission route of ESBL-producing Escherichia coli and ESBLs in the European Union (EU ...
I. Bergšpica, G. Kaprou, E. Alexa, M. Prieto, A. Álvarez‐Ordoñez   +4 more
semanticscholar   +1 more source