Results 21 to 30 of about 804,660 (312)

Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies

open access: yesScience, 2020
An antibody cocktail against SARS-CoV-2 There is an urgent focus on antibodies that target the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral spike and prevent the virus from entering host cells. Hansen et al.
A. Baum   +15 more
semanticscholar   +1 more source

SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

open access: yesNature, 2021
An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape1–3, have activity against diverse sarbecoviruses4–7, and be highly protective through viral neutralization8–11 and effector functions12,13.
Tyler N. Starr   +56 more
semanticscholar   +1 more source

Heterelogous expression of mutated HLA-G decreases immunogenicity of human embryonic stem cells and their epidermal derivatives

open access: yesStem Cell Research, 2014
Human embryonic stem cells (hESCs) are capable of extensive self-renewal and expansion and can differentiate into any somatic tissue, making them useful for regenerative medicine applications.
Longmei Zhao   +2 more
doaj   +1 more source

Evaluation of a modified method for the detection of Cryptosporidium oocysts on spinach leaves

open access: yesFood and Waterborne Parasitology, 2020
Despite the infection risk associated with the consumption of contaminated food, techniques for recovering and detecting Cryptosporidium oocysts from fruit and vegetables are generally inadequate due to the variable recovery efficiencies and high reagent
Romy Razakandrainibe   +10 more
doaj   +1 more source

Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

open access: yesbioRxiv, 2021
Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis for COVID-19. However, ongoing evolution of SARS-CoV-2 can render monoclonal antibodies ineffective.
Tyler N. Starr   +3 more
semanticscholar   +1 more source

Retrospective analysis of SARS-CoV-2 omicron invasion over delta in French regions in 2021–22: a status-based multi-variant model

open access: yesBMC Infectious Diseases, 2022
Background SARS-CoV-2 is a rapidly spreading disease affecting human life and the economy on a global scale. The disease has caused so far more then 5.5 million deaths.
Thomas Haschka   +4 more
doaj   +1 more source

Organization of escapes from detention facility in the Tambov governorate at the beginning of the 20th century

open access: yesВестник Тамбовского университета. Серия: Гуманитарные науки, 2023
Importance. The relevance of the chosen research topic is due to the scientific study of the effectiveness of the ongoing penitentiary policy at the beginning of the 20th century in Tsarist Russia and Russia during the Civil War.Materials and methods ...
N. A. Kozhukhov
doaj   +1 more source

Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies

open access: yesNature Communications, 2021
Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals previously infected with SARS-CoV-2, but the relative contributions of these different antibody classes to the polyclonal response remains unclear.
Allison J. Greaney   +18 more
semanticscholar   +1 more source

SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients

open access: yesScience immunology, 2021
Infection- or vaccination-induced SARS-CoV-2 S-specific CD4+ T cells are indifferent to the S mutations of variants of concern. The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has raised concern about potential immune ...
D. Geers   +24 more
semanticscholar   +1 more source

Phlebotomine sandflies (Diptera, Psychodidae) from the Ankarana tsingy of northern Madagascar: inventory and description of new taxa

open access: yesParasite, 2019
An inventory of Phlebotomine sandflies was carried out in the Ankarana tsingy located in far northern Madagascar. A total of 723 sandflies were used for morphological, morphometric, and molecular studies (sequencing of partial cytochrome B (mtDNA) and ...
Blavier Antoine   +7 more
doaj   +1 more source

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