Results 41 to 50 of about 621,777 (315)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Escape-strategy data

, 2017
Escape behavior data ( FID and flight distance) of grasshoppers in a urban ...
Pim Edelaar (645112), Adrián Baños-Villalba (3664528), David P. Quevedo (5015759), Baños-Villalba, Adrián, Edelaar, Pim, Quevedo, David P.   +5 more
core   +1 more source

Variation in Predator Recognition Across Three Species of Jumping Spiders (Salticidae) [PDF]

Animal Behavior and Cognition
The ability to recognize threats and to respond in a timely and appropriate manner carries significant benefits. Depending on the recognition task, this can be cognitively demanding.
Janka Plate, Daniela C. Rößler
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Typographical Artifices in Nicola Barker’s H(A)PPY

Ars & Humanitas, 2022
In Nicola Barker’s novel H(A)PPY the individual’s struggle to resist and escape from a virtualized, monitored and uniform world is masterfully reflected typographically.
Mihaela Culea, Andreia Irina Suciu
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Escape Velocity Dance Company Presents: Emerge

, 2021
Escape Velocity is a student run dance company that provides students the opportunity to choreograph for, dance in, and/or produce performances for the Ursinus College community throughout the year.
Troupe, Escape Velocity Dance
core   +1 more source

G2019S selective LRRK2 kinase inhibitor abrogates mitochondrial DNA damage

npj Parkinson's Disease
Pathogenic mutations in LRRK2 cause Parkinson’s disease (PD). The G2019S variant is the most common, which results in abnormally high kinase activity. Compounds that target LRRK2 kinase activity are currently being developed and tested in clinical trials.
Nicholas Pena, Tara Richbourg, Claudia P. Gonzalez-Hunt, Rui Qi, Paul Wren, Carrolee Barlow, Natalie F. Shanks, Holly J. Carlisle, Laurie H. Sanders   +8 more
doaj   +1 more source

Feeding behaviour of young larvae of Pieris rapae crucivora (Lepidoptera: Pieridae) and its effect on parasitism by Cotesia glomerata (Hymenoptera: Braconidae)

European Journal of Entomology, 2018
We investigated the effect of the feeding behaviour of young larvae of Pieris rapae crucivora Boisduval (Pieridae) on parasitism by the parasitoid wasp, Cotesia glomerata (L.) (Braconidae).
Aya NAKAYAMA, Keiji NAKAMURA, Jun TAGAWA
doaj   +1 more source

Escaping the Cycle

Mind, 2021
Abstract I present a decision in which causal decision theory appears to violate the independence of irrelevant alternatives (IIA) and normal-form extensive-form equivalence (NEE). I show that these violations lead to exploitable behaviour and long-run poverty. These consequences appear damning, but I urge caution.
openaire   +3 more sources