Results 201 to 210 of about 4,578 (289)

Comparative Response of Canine and Human Osteosarcoma Tumour Cell Lines to Molecularly Targeted Anticancer Agents at Clinically Relevant Exposures With Analysis of Genomic Biomarkers

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT Osteosarcoma (OSA) is a primary bone tumour occurring in children but is also prevalent in large breed dogs. Canine OSA (cOSA) has long been viewed as analogous to human OSA (hOSA) with cOSA serving as a surrogate for development of therapeutic approaches to treat the rarer human form.
Daniel L. Gustafson   +5 more
wiley   +1 more source

Phylogeny and Species Delimitation in the Land Snail Genus Chilostoma (Gastropoda: Helicidae) and East–West Alpine Disjunctions

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Chilostoma includes large, mostly rock‐dwelling snail species, widespread in the European Alps and the Apennines in Italy. We analysed the phylogenetic relationships and the species delimitation of the Chilostoma (Chilostoma) species based on genomic ddRAD loci. The Chilostoma (Chilostoma) taxa form three sister pairs. Chilostoma achates and C.
Elisa Becher, Bernhard Hausdorf
wiley   +1 more source

Progress and Challenges in Phylogenomics and Genomics of Lophotrochozoa/Spiralia

open access: yesZoologica Scripta, EarlyView.
ABSTRACT Lophotrochozoa is one of the three major bilaterian groups comprising more than half of the bilaterian phyla. Lophotrochozoa includes among others Mollusca, Annelida, Platyhelminthes and Rotifera. Despite representing such a large proportion of animal diversity, they are historically understudied and genomic resources have been scarce. However,
Torsten H. Struck
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford   +9 more
wiley   +1 more source

Hypoxia and the cytoskeleton

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Modelling Motion‐Induced Signal Corruption in Steady‐State Diffusion MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 1, Page 66-82, July 2026.
ABSTRACT Purpose Diffusion‐weighted steady‐state free precession (DW‐SSFP) is a diffusion imaging sequence achieving high SNR efficiency. A key challenge for in vivo DW‐SSFP is the sequence's severe motion sensitivity, currently limiting investigations to low or no motion regimes.
Benjamin C. Tendler   +3 more
wiley   +1 more source

Non-gonadal PIWI protein, Aubergine, regulates regenerative stem cell proliferation and tumourigenesis in theDrosophilaadult intestine

open access: yes
Bellec K   +10 more
europepmc   +1 more source

Autophagy in adult stem cell homeostasis, aging, and disease therapy. [PDF]

open access: yesCell Regen
Zhao K   +5 more
europepmc   +1 more source

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