Results 31 to 40 of about 10,382 (192)

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Epidemiological and clinical features of scrub typhus in Odisha, Eastern India

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2019
Introduction: Scrub typhus is a mite-borne bacterial infection of humans caused by Orientia tsutsugamushi that presents with prolonged fever unless suspected early.
Palash Das, Divya Singh, Mirabai Das, Rajesh Kumar Nayak, Nirmal Kumar Mohakud   +4 more
doaj   +1 more source

Eschar: an important clue to diagnosis [PDF]

BMJ Case Reports, 2013
A 35-year-old woman, a farmer by occupation, resident of Uttranchal (a sub-Himalayan area) in India, presented in the emergency department with complaints of fever for 1 week and breathlessness for 2 days. Fever was high grade, intermittent, associated with chills, myalgia and headache.
Deepak, Sundriyal, Naveen, Kumar, Arun, Chandrasekharan, Brijesh, Sharma   +3 more
openaire   +2 more sources

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

A Photothermally Amplified Enzyme–Nitric Oxide Co‐Regulatory System Reprograms Pathological ECM–Fibroblast Crosstalk to Alleviate Hypertrophic Scarring

Advanced Science, EarlyView.
An enzyme–nitric oxide (NO) co‐regulatory strategy reprograms pathological extracellular matrix (ECM)–fibroblast crosstalk in hypertrophic scars. Enzymatic degradation of pre‐existing ECM relieves aberrant mechanical cues, while NO‐mediated fibroblast phenotypic modulation restrains excessive collagen synthesis.
Junzhe Fu, Fan Jia, Yixian Mu, Wanzhe Liu, Dingqi Tang, Qiao Jin, Jian Ji, Youxiang Wang   +7 more
wiley   +1 more source

Scrub Typhus with Acute Respiratory Distress Syndrome (ARDS) and its Management in Intensive Care Unit: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2015
Scrub typhus is zoonotic disease caused by Orientia tsutsugamushi (O tsutsugamushi). It is transmitted to humans by the bite of trombiculid mite larvae (chiggers). It is a re-emerging infectious disease in India.
Srinivas Sankuratri, Pavani Kalagara, Kartika Balaji Samala, Prabhakar Krishna Veledandi, Srinadh Babu Atiketi   +4 more
doaj   +1 more source

Engineering programmable peptide hydrogels for chronic refractory wounds: A mechanism‐driven framework

BMEMat, EarlyView.
To break the self‐perpetuating pathology of chronic wounds, we propose a mechanism‐driven engineering framework for peptide‐based hydrogels. This review elucidates a hierarchical strategy—from molecular design to intelligent, multi‐functional systems—that enables these programmable biomaterials to dynamically intervene in key pathological loops and ...
Xiaoyu Lv, Xinyi Chao, Jiamin Zhang, Jianfeng Liu   +3 more
wiley   +1 more source

Scrub typhus: A case report from Bangladesh

APIK Journal of Internal Medicine, 2021
Scrub typhus is an acute febrile illness caused by a Gram-negative obligate intracellular bacterium named Orientia tsutsugamushi. Although this zoonotic disease is common in tropical and subtropical regions, it is often underreported in Bangladesh.
Shaila Rahman, Tamanna Bahar
doaj   +1 more source

Mechanistic Evaluation of Luteolin in Wound Healing of Diabetic Foot Ulcer via Nrf2 Signaling

Phytotherapy Research, EarlyView.
Proposed mechanism by which Luteolin (LU) promotes diabetic foot ulcer healing. LU attenuates hyperglycemia‐induced oxidative stress and lipid peroxidation, improves endothelial cell viability, and suppresses ferroptosis through Nrf2‐dependent antioxidant signaling, thereby accelerating angiogenesis and wound repair. ABSTRACT Diabetic foot ulcers (DFUs)
Muhammed Yusuf, Ayfer Busra Benkli, Ramiz Yusuf   +2 more
wiley   +1 more source

A Rare Case of Scrub Typhus Presenting as Pre Septal Cellulitis [PDF]

Journal of Clinical and Diagnostic Research
Scrub typhus, a vector-borne disease caused by Orientia tsutsugamushi, is known for its diverse clinical manifestations. However, atypical presentations, such as preseptal cellulitis, are rarely documented and pose diagnostic challenges.
Aishwarya M Angadi, Nagyang Dani, (Col) OK Radhakrishnan, 2nd Year Resident, Department of Ophthalmology, Dr. D. Y. Patil Medical Hospital and Research Centre, Pune, Maharashtra, India.   +3 more
doaj   +1 more source