Results 211 to 220 of about 1,472,388 (311)

Constraint of Lignin–Carbohydrate Complex Orchestrated on Polyphenol in Oil–Water Interface Targeting Ulcerative Colitis Therapy

Advanced Science, EarlyView.
This study constructed the W1/O/W2 emulsion–based targeted therapy delivery system for ulcerative colitis (UC) utilizing LCC as surfactant for the first time. This multifunctional emulsion offered certain therapeutic advantages for UC, including targeted colonic delivery of active compounds, synergistic modulation of gut microbiota through combined ...
Qian Wu, Xingyu Zhang, Jingjia Zhang, Gaohui Huang, Chen Zhou, Chunlin Li, Xiaojun Huang, Jianbo Xiao, Nianjie Feng, Yuanbin She   +9 more
wiley   +1 more source

CRISPR/Cas13a: Compensatory Target Activation Mechanism

Advanced Science, EarlyView.
CRISPR/Cas13a‐CTAM as a novel compensatory target activation mechanism that enables synergistic activation of Cas13a via two independently editable short RNA effectors. This dual‐effector system maintains enzymatic activity comparable to traditional single‐effector while significantly enhancing flexibility, sensitivity, and application scope.
Bowen Jiang, Tenghua Zhang, Yao Lu, Shujun Zhou, Wenjing Xiao, Shuming Pan, Nan Shi, Yan Sheng, Jiaming Hu   +8 more
wiley   +1 more source

Elevating Haloperoxidase Expression in Escherichia coli through Fusion with a Formate Oxidase. [PDF]

Chembiochem
Pothuizen A, van Hengst JMA, Wever R, Hagedoorn PL, Hollmann F.   +4 more
europepmc   +1 more source

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

Shiga Toxin-Producing Escherichia coli Outbreak in Canadian Daycare Centers.

JAMA Netw Open
Eltorki M, Ajayi OO, Seok J, Xie J, Rizzuti FA, Berenger BM, Tarr PI, Pavia AT, Snedeker K, Grisaru S, Vanderkooi OG, Chui L, Tarr GAM, Vomiero G, Freedman SB.   +14 more
europepmc   +1 more source

Environmental isolation and characterization of Escherichia coli phages from Burkina Faso. [PDF]

BMC Microbiol
Ouédraogo N, Zerbo M, Traoré AK, Addablah A, Soro O, Kakou-Ngazoa S, Barro N.   +6 more
europepmc   +1 more source

Insights into enterotoxigenic Escherichia coli diversity in Bangladesh utilizing genomic epidemiology [PDF]

, 2017
A Bankevich, A Mentzer von, A Sjoling, AC Vicente, AM Almeida de, AR Quinlan, AR Wattam, C Lindenthal, CA Jacobi, D Hernandez, DA Rasko, DA Rasko, DG Evans, DJ Ingle, EW Myers, F Canto Del, F Canto Del, F Qadri, GB Lindblom, GP Munson, H Steinsland, HL DuPont, HL DuPont, I Bolin, I Letunic, JM Fleckenstein, JM Fleckenstein, JM Fleckenstein, JS Farris, JW Sahl, JW Sahl, JW Sahl, JW Sahl, JW Sahl, K Hayashi, K Roy, K Roy, K Roy, K Schliep, KL Kotloff, LC Crossman, M So, M So, MA Lasaro, MN Price, MS Donnenberg, P Kumar, Q Luo, R Lozano, RA Finkelstein, RA Nada, RB Sack, RC Edgar, RI Walker, S Schubert, SF Altschul, SK Patel, SM Turner, T Seemann, T Wirth, TH Hazen, W Gaastra, WHO   +62 more
core   +2 more sources

Programmable Semi‐Interpenetrating Living Materials With Robust Stability for Versatile Bioremediation and Biotherapeutics

Advanced Science, EarlyView.
A semi‐interpenetrating engineered living material (sIHSELM), fabricated via thermosensitive hydroxybutyl chitosan and covalent protein self‐assembly, demonstrates exceptional mechanical properties and environmental stability. Shielding bacteria from harsh conditions, sIHSELM exhibits remarkable efficacy in ulcerative colitis treatment and pollutants ...
Zixian Bao, Shengfeng Yang, Dandan Hu, Jiezheng Liu, Bo Jiang, Xinyue Sui, Qingsheng Qi, Lai Li, Guang Zhao   +8 more
wiley   +1 more source

Migratory Birds Facilitate the Spread of Multidrug-Resistant Pathogenic Escherichia coli in Tanguar Haor of Bangladesh. [PDF]

Environ Microbiol Rep
Khatun MN, Chakraborty S, Akter T, Ifte JS, Begum JA, Islam MA, Parvin R, Hossain MT, Chowdhury EH.   +8 more
europepmc   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source