Results 291 to 300 of about 1,614,971 (341)
Zhan et al. demonstrate the vital role of NAT10‐catalyzed ac4C modification in regulating autophagy‐associated lysosomal acidification. They uncover the clinical and biological significance of ATP6V0E1, an important v‐ATPase assembly subunit, in tumor metastasis, particularly in the malignant progression of ESCC.
Yu‐Juan Zhan+23 more
wiley +1 more source
The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong+27 more
wiley +1 more source
Run-and-tumble dynamics of <i>Escherichia coli</i> is governed by its mechanical properties. [PDF]
Wu-Zhang B+6 more
europepmc +1 more source
Inhibition of RNase to Attenuate Fungal‐Manipulated Rhizosphere Microbiome and Diseases
Fusarium graminearum uses its virulence effector Fg12, a fungal RNase, to manipulate the host rhizosphere microbiome and promote infection. Guanosine monophosphate (GMP) blocks Fg12's RNase activity. This reveals a key pathogen‐microbiota interaction mechanism and proposes GMP as a targeted strategy to disarm this core fungal effector, offering a ...
Bo Yang+13 more
wiley +1 more source
Sulfide-Responsive Transcription Control in Escherichia coli. [PDF]
Hori K, Balasubramanian R, Masuda S.
europepmc +1 more source
Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment
A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen+7 more
wiley +1 more source
Isolation and identification of bacteriophage against Escherichia coli ATCC 25922 and their biofilm Inhibition studies. [PDF]
Sivakumar L+11 more
europepmc +1 more source
Hijacking Host Kinase PIM1: A β‐Coronavirus (OC43) strategy to degrade IFNAR1 and evade antiviral immunity. Human β‐coronaviruses (OC43) exploit the proto‐oncoprotein PIM1 kinase to sabotage innate immunity. Viral RNA/proteins upregulate PIM1, which phosphorylates E3 ligase β‐TrCP1.
Qianya Wan+16 more
wiley +1 more source
Complete genome sequences of <i>Escherichia coli</i> phages Huey, Dewey, and Louie. [PDF]
Maffei E, Willi L, Harms A.
europepmc +1 more source
Carbon dots (CDs) are incorporated into ZIF‐8 to synthesize CDs@ZIF‐8 nanocomposites, which exhibit dual photodynamic enhanced antimicrobial properties. This enhancement is due to the narrow bandgap of CDs@ZIF‐8, which facilitates interfacial electronic transfer, resulting in increased reactive oxygen species. Microfluidic blow spinning is then used to
Yongrui Ti+10 more
wiley +1 more source