Results 101 to 110 of about 15,562 (220)

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

open access: yesAdvanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang   +6 more
wiley   +1 more source

SUMOylation of SETD8 Promotes Tumor Growth by Methylating and Stabilizing MYC in Bladder Cancer

open access: yesAdvanced Science, EarlyView.
In bladder cancer (BC), MYC serves as a novel substrate of SETD8 to be methylated at lysine 412, which enhances MYC protein stability by preventing the CHIP‐mediated degradation and ultimately promotes tumor growth. SUMOylation of SETD8 leads to SETD8 stabilization and enhances MYC methylation.
Xia Zhang   +11 more
wiley   +1 more source

Functional Divergence of Plant‐Derived Thaumatin‐Like Protein Genes in Two Closely Related Whitefly Species

open access: yesAdvanced Science, EarlyView.
Two closely related whitefly species, Trialeurodes vaporariorum and Bemisia tabaci, are found to each possess a plant‐derived TLP gene, but with entirely different functions. This finding of functional divergence challenges the notion that HGT genes maintain similar functions across species and shows that they can follow unique evolutionary paths that ...
Yuan Hu   +12 more
wiley   +1 more source

Comparison of Clinical Scores for Predicting Stroke‐Associated Pneumonia After Acute Ischemic Stroke

open access: yesAGING MEDICINE, EarlyView.
Our study compared the discrimination and calibration of the Kwon Pneumonia Score, A2DS2 score, PANTHERIS score, AIS‐APS score, ISAN score, and PASS score in SAP identification; of these, the AIS‐APS score showed the best performance. ABSTRACT Objectives To compare the discrimination and calibration of six risk scoring systems in the assessment of ...
Linlin Wang   +8 more
wiley   +1 more source

Ultrafine‐Mn‐Loaded N,O‐Doped Nanocarbon via Mott‒Schottky Effect for Photo‐Enhanced Antibacterial Therapy and Wound Healing

open access: yesAggregate, EarlyView.
Herein, we used the Mott–Schottky effect to synthesize an ultrafine‐Mn‐loaded N,O‐doped porous nanocarbons (Mn‐PNCs) nanozyme. The fabricated Mn‐PNCs nanozyme using a sustainable and efficient heteroatom‐doped strategy exhibited excellent photothermal‐enhanced, peroxidase‐like activity, thereby contributing to effective antibacterial treatment for ...
Xueyu Jiang   +5 more
wiley   +1 more source

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