Results 171 to 180 of about 1,005,431 (399)

Role of Recent Therapeutic Applications and the Infection Strategies of Shiga Toxin-Producing Escherichia coli [PDF]

open access: gold, 2021
Su-Bin Hwang   +6 more
openalex   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

open access: yesAdvanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang   +9 more
wiley   +1 more source

Bacterial pathogens in orthopedic implant infection and their resistance to antimicrobial therapy: A retrospective analysis

open access: yesJournal of Orthopaedic Reports
Background: Orthopedic implant infections pose a significant challenge in healthcare due to increasing rates and the emergence of multidrug-resistant (MDR) pathogens.
Ameer Hamza Mahmood Ul Hassan   +3 more
doaj   +1 more source

Unravelling the Differential Host Immuno-Inflammatory Responses to Staphylococcus aureus and Escherichia coli Infections in Sepsis. [PDF]

open access: yesVaccines (Basel), 2022
Gupta E   +7 more
europepmc   +1 more source

Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li   +11 more
wiley   +1 more source

Antibiotic Consumption in Hospitals and Resistance Rate of Klebsiella pneumoniae and Escherichia coli in Montenegro

open access: yesActa Clinica Croatica, 2020
Inappropriate use of antibiotics leads to an increase in antibiotic resistance. Infections caused by antibiotic-resistant gram-negative bacteria are a serious threat to public health.
Gordana Mijović   +4 more
doaj  

A low-cost recombinant glycoconjugate vaccine confers immunogenicity and protection against enterotoxigenic Escherichia coli infections in mice. [PDF]

open access: yesFront Mol Biosci, 2023
Williams AJ   +11 more
europepmc   +1 more source

Risk factors for sporadic cases of Escherichia coli O157 infection: the importance of contact with animal excreta [PDF]

open access: bronze, 2001
Mary E. Locking   +7 more
openalex   +1 more source

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu   +11 more
wiley   +1 more source

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