Results 181 to 190 of about 1,560,602 (304)

Seven-Year Surveillance and AI-Based Forecasting of Antimicrobial Resistance in Pediatric <i>Escherichia coli</i> Infections in Northern China (2018-2024). [PDF]

Infect Drug Resist
Chen Y, Song Z, Di R, Zhao Q, Liu J, Song H, Wang J, Chen Y.   +7 more
europepmc   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Burden of <i>Shigella</i> and enterotoxigenic <i>Escherichia coli</i> infections among children under 5 years in Ethiopia, Kenya and Malawi: a systematic review and meta-analysis. [PDF]

BMJ Glob Health
Mwendera CA, Yilma M, Wairimu C, Kering K, Mwinjiwa E, Kariuki JN, Asrat D, Mekasha A, Msefula C, Kariuki S, Cornick J, Clough H, French N, Pitzer V, Jere KC, Hungerford D, GHRG-GI Consortium, GHRG-GI Consortium .   +17 more
europepmc   +1 more source

Unveiling the Taxonomic Diversity and Unprecedented Biosynthetic Treasure of the Phylum Myxococcota

Advanced Science, EarlyView.
Natural products remain vital sources of therapeutics, and the phylum Myxococcota constitutes an especially rich reservoir for them. Based on decades of microbiological efforts, we present 154 new Myxococcota genomes and revise taxonomy quadrupling the number of families and genera.
Amay Ajaykumar Agrawal, Ronald Garcia, Guangyi Chen, Chantal D. Bader, Peter Sullivan, Alexander Popoff, Daniel Krug, Maja Hunter, Sebastian Walesch, Emilia Oueis, Christine Frank, Haowen Zhao, Joachim J. Hug, Sebastian Keller, Pascal Hirsch, Azat Tagirdzhanov, Tatiana Malygina, Mary Victory E. Gutierrez, Alexey Gurevich, Judith Boldt, Boyke Bunk, Jörg Overmann, Ulrich Nübel, Andreas Keller, Olga V. Kalinina, Rolf Müller   +25 more
wiley   +1 more source

Pathogenicity of mcr-1-positive Escherichia coli from human infections

The Lancet Microbe, 2020
Cong Shen, Lan-Lan Zhong, Yohei Doi, Nicole Stoesser, Furong Ma, Zihan Zhao, Bin Yan, Guo-Bao Tian   +7 more
doaj   +1 more source

Synthesis of polymeric nanoparticles by double emulsion and pH-driven: encapsulation of antibiotics and natural products for combating Escherichia coli infections. [PDF]

Appl Microbiol Biotechnol
de Almeida Campos LA, de Souza JB, de Queiroz Macêdo HLR, Borges JC, de Oliveira DN, Cavalcanti IMF.   +5 more
europepmc   +1 more source

Clinical and Molecular Epidemiology of Extended-Spectrum Beta-Lactamase-Producing Escherichia Coli Infections in Metro Detroit: Early Dominance of the ST-131 Clone. [PDF]

Infect Dis Ther, 2020
Mills JP, Kaye KS, Evans R, Salzman E, Pogue J, Hayakawa K, Marchaim D, Awasthy P, Salim M, Martin ET.   +9 more
europepmc   +1 more source

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

Advanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang, Zhanzhi Liu, Ying Xu, Mingjing Sun, Guangzhen Zhou, Deming Rao, Xiaoqian Chen, Sheng Wang, Zhigang Li, Yan Huang, Jing Wu   +10 more
wiley   +1 more source

ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER–Mitochondria Contact Sites

Advanced Science, EarlyView.
ABSTRACT Mitochondrial transport and distribution are crucial for cellular homeostasis, yet whether and how they are regulated by endoplasmic reticulum (ER)–mitochondria contact sites remains unclear. Here, we demonstrate that the ER protein atlastin‐2 (ATL2) orchestrates mitochondrial transport and distribution by promoting assembly of the transport ...
Yiru Cheng, Peiyuan Chai, Xiayuhe Pei, Yiwen Chen, Xiaoshuai Huang, Bei Liu, Yiqian Wu, Junlin Teng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Non-O157 Shiga Toxin-Producing Escherichia coli Infections in Europe

Emerging Infectious Diseases, 1997
Alfredo Caprioli, Alberto E. Tozzi, Gianfranco Rizzoni, Helge Karch   +3 more
doaj   +1 more source