Results 171 to 180 of about 491,044 (305)

ZDHHC17‐Mediated CDK4 Palmitoylation Drives Cell Cycle Progression and Orchestrates Cancer Immune Surveillance

open access: yesAdvanced Science, EarlyView.
ZDHHC17 palmitoylates CDK4, which together with TRAF6‐mediated ubiquitination, drives cell cycle progression and immune surveillance, revealing a rational combination of CDK4 inhibitors with immune checkpoint blockers for ZDHHC17‐driven cancers. ABSTRACT Uncontrolled cell cycle progression is a hallmark of cancer, tightly regulated by both intrinsic ...
Zekang Wang   +7 more
wiley   +1 more source

Predicting Adverse Outcomes for Shiga Toxin-Producing Escherichia coli Infections in Emergency Departments. [PDF]

open access: yesJ Pediatr, 2021
Lin CY   +34 more
europepmc   +1 more source

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe   +8 more
wiley   +1 more source

Evaluation of the health and healthcare system burden due to antimicrobial-resistant Escherichia coli infections in humans: a systematic review and meta-analysis. [PDF]

open access: yesAntimicrob Resist Infect Control, 2020
MacKinnon MC   +6 more
europepmc   +1 more source

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo   +38 more
wiley   +1 more source

Recent Trends in Metabolomics by NMR Spectroscopy

open access: yesAngewandte Chemie, EarlyView.
AI tools were applied to analyze more than 5 000 publications indexed in Scopus (2018–2025), identifying key trends and research directions in NMR‐based metabolomics. The artificial intelligence‐assisted workflow classified papers into six main fields of application, human health, food and nutrition, veterinary science, plants, environment, and ...
Giorgio Di Paco   +6 more
wiley   +2 more sources

Rapid formulation of a genetically diverse phage cocktail targeting uropathogenic Escherichia coli infections using the UTI89 model. [PDF]

open access: yesSci Rep
Kongsomboonchoke P   +6 more
europepmc   +1 more source

Measures used to assess the burden of ESBL-producing Escherichia coli infections in humans: a scoping review. [PDF]

open access: yesJAC Antimicrob Resist, 2021
McDonald KL   +6 more
europepmc   +1 more source

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