Results 201 to 210 of about 482,887 (312)

Mechano‐Bactericidal Surfaces Achieved by Epitaxial Growth of Metal–Organic Frameworks

open access: yesAdvanced Science, EarlyView.
Mechano‐bactericidal surfaces based on metal–organic frameworks (MOFs) are designed using a MOF‐on‐MOF strategy. Two methods of MOF surface assembly, in situ growth and ex situ dropcasting, are applied. Distinct mechano‐bactericidal actions are discussed, including stretching, impaling, and mechanical injury. Abstract Mechano‐bactericidal (MB) surfaces
Zhejian Cao   +7 more
wiley   +1 more source

Synthesis of polymeric nanoparticles by double emulsion and pH-driven: encapsulation of antibiotics and natural products for combating Escherichia coli infections. [PDF]

open access: yesAppl Microbiol Biotechnol
de Almeida Campos LA   +5 more
europepmc   +1 more source

CLAE: A High‐Fidelity Nanopore Sequencing Strategy for Read‐Level Viral Variant Detection and Environmental RNA Virus Discovery

open access: yesAdvanced Science, EarlyView.
High‐fidelity Nanopore sequencing offers a cost‐effective, portable path to uncovering viral dark matter in complex environments—but suffers from severe read‐length bias, low throughput, and limited accuracy. This study traces these limitations to core biochemical barriers and introduces CLAE, a foundational high‐fidelity platform that enables accurate,
Hannah Yu   +14 more
wiley   +1 more source

Molecular Chain Elongation Mechanism for n‐Caproate Biosynthesis by Megasphaera Hexanoica

open access: yesAdvanced Science, EarlyView.
The medium‐chain carboxylate‐producing microbe Megasphaera hexanoica is analyzed through genomics, transcriptomics, and metabolic engineering. The n‐caproate biosynthetic pathway is reconstructed in Escherichia coli, highlighting MhTHL as a key β‐ketothiolase. Structural analysis and mutagenesis reveal that MhTHL has a distinct substrate‐binding pocket,
Byoung Seung Jeon   +8 more
wiley   +1 more source

Two marine sulfur-reducing bacteria co-culture is essential for productive infection by a T4-like Escherichia coli-infecting phage

open access: gold
Adriele Jéssica do Carmo Santos   +6 more
openalex   +1 more source

Painting Peptides With Antimicrobial Potency Through Deep Reinforcement Learning

open access: yesAdvanced Science, EarlyView.
AMPainter is a powerful design model for ’painting’ the antimicrobial potency on any given peptide sequence, based on the strategy of virtual directed evolution and deep reinforcement learning. Abstract In the post‐antibiotic era, antimicrobial peptides (AMPs) are considered ideal drug candidates because of their lower likelihood of inducing resistance.
Ruihan Dong, Qiushi Cao, Chen Song
wiley   +1 more source

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