Results 101 to 110 of about 729,912 (260)

A novel plant E3 ligase stabilizes Escherichia coli heat shock factor σ32

open access: yesScientific Reports, 2017
The heat shock response is crucial for organisms against heat-damaged proteins and maintaining homeostasis at a high temperature. Heterologous expression of eukaryotic molecular chaperones protects Escherichia coli from heat stress.
Yulong Niu   +8 more
doaj   +1 more source

Engineering of Therapeutic Proteins Production in Escherichia coli [PDF]

open access: yesCurrent Pharmaceutical Biotechnology, 2011
Low cost and simplicity of cultivating bacteria make the E. coli expression system a preferable choice for production of therapeutic proteins both on a lab scale and in industry. In addition straightforward recombinant DNA technology offers engineering tools to produce protein molecules with modified features. The lack of posttranslational modification
openaire   +2 more sources

Posttranslational Modifications of Ribosomal Proteins in Escherichia coli

open access: yesActa Naturae, 2011
А number of ribosomal proteins inEscherichia coliundergo posttranslational modifications. Six ribosomal proteins are methylated (S11, L3, L11, L7/L12, L16, and L33), three proteins are acetylated (S5, S18, and L7), and protein S12 is methylthiolated. Extra amino acid residues are added to protein S6. С-terminal amino acid residues are partially removed
Nesterchuk, M.   +2 more
openaire   +4 more sources

RNA-dependent proteome solubility maintenance in Escherichia coli lysates analysed by quantitative mass spectrometry: Proteomic characterization in terms of isoelectric point, structural disorder, functional hub, and chaperone network

open access: yesRNA Biology
Protein aggregation, a consequence of misfolding and impaired proteostasis, can lead to cellular malfunctions such as various proteinopathies.
Chan Park   +6 more
doaj   +1 more source

Evolvability of Chaperonin Substrate Proteins [PDF]

open access: yes, 2009
Molecular chaperones ensure that their substrate proteins reach the functional native state, and prevent their aggregation. Recently, an additional function was proposed for molecular chaperones: they serve as buffers (_capacitors_) for evolution by ...
Emanuele Raineri   +3 more
core   +1 more source

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