The effects of escitalopram on myocardial apoptosis and the expression of Bax and Bcl-2 during myocardial ischemia/reperfusion in a model of rats with depression [PDF]
BackgroundMajor depressive disorder (MDD) is an independent risk factor for coronary heart disease (CHD), and influences the occurrence and prognosis of cardiovascular events.
Berk,M, Chai,F, Liu,X, Wang,Y, Zhang,H
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Escitalopram-Induced Hyperprolactinemic Galactorrhea
Galactorrhea is milky secretions from the breast in women who have not breast-fed for a year. Escitalopram, a selective serotonin reuptake inhibitor (SSRI), owing to its potency and tolerance, is regarded as the primary line drug in the management of ...
Deepthi Yedla, Vijayan Sharmila
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The FDA “black box” warning on antidepressant suicide risk in young adults: More harm than benefits? [PDF]
The decision made in the year 2004 by the U.S. Food and Drug Administration (FDA) to require a boxed warning on antidepressants regarding the risk of suicidality in young adults still represents a matter of controversy.
Anastasia A. +12 more
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Objective To report side effect frequency and severity in patients with major depressive disorder (MDD) receiving escitalopram and aripiprazole adjunctive therapy and to examine whether pretreatment anxious depression is associated with the number and ...
Caroline W. Espinola +14 more
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Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]
In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P +8 more
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Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA +2 more
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Estimation of the optimal dosing regimen of escitalopram in dogs : a dose occupancy study with [11C]DASB [PDF]
Although the favourable characteristics of escitalopram as being the most selective serotonin reuptake inhibitor and having an increased therapeutic efficacy via binding on an additional allosteric binding site of the serotonin transporter, its dosing ...
Baeken, Chris +11 more
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Introduction Despite replicated cross-sectional evidence of aberrant levels of peripheral inflammatory markers in individuals with major depressive disorder (MDD), there is limited literature on associations between inflammatory tone and response to ...
M. I. Husain +16 more
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Incomplete Resolution of Deep Vein Thromboses during Rivaroxaban Therapy. [PDF]
We present the case of a patient with a deep vein thrombosis (DVT) who failed rivaroxaban therapy. Our patient initially presented with left lower extremity edema, erythema, and pain.
Adashek, Jacob +6 more
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Evidence suggests that selective serotonin reuptake inhibitors (SSRIs) reorganize neural networks via a transient window of neuroplasticity. While previous findings support an effect of SSRIs on intrinsic functional connectivity, little is known ...
Eóin N. Molloy +12 more
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