Results 51 to 60 of about 32,801 (227)

A Study about Escitalopram Versus Citalopram in the Treatment of Depressive Disorders [PDF]

مجلة الموصل للتمريض, 2015
Background and aim: To compare the therapeutic efficacy , time onset of action, and patient compliance of escitalopram versus citalopram in the treatment of depressive disorders (DD) in Kirkuk City _Iraq Materials and Method: 100 outpatients complaining
Jasim M. Shindi, Ali Talib Gallib
doaj   +1 more source

Escitalopram enhances synchrony of brain responses during emotional narratives in patients with major depressive disorder

NeuroImage, 2021
One-week treatment with escitalopram decreases amygdala responses to fearful facial expressions in depressed patients, but it remains unknown whether it also modulates processing of complex and freely processed emotional stimuli resembling daily life ...
Emma Komulainen, Enrico Glerean, Roope Heikkilä, Lauri Nummenmaa, Tuukka T. Raij, Erkki Isometsä, Jesper Ekelund   +6 more
doaj   +1 more source

Effects of the prophylactic use of escitalopram on the prognosis and the plasma copeptin level in patients with acute cerebral infarction [PDF]

Brazilian Journal of Medical and Biological Research, 2020
This study aimed to investigate whether the routine administration of escitalopram for three months would improve the prognosis of patients with ischemic stroke and decrease the plasma copeptin level. A total of 97 patients with acute cerebral infarction
Jin-Xia Cao, Li Liu, Yun-Tao Sun, Qing-Hong Zeng, Yan Wang, Jie-Chun Chen   +5 more
doaj   +1 more source

Differential Effects of Single-Dose Escitalopram on Cognitive and Affective Interference during Stroop Task [PDF]

, 2014
Background and objective: Our aim was to study the regulatory role of serotonin [(5-hydroxytryptamine (5-HT)] on two key nodes in the cognitive control networks – the anterior cingulate cortex (ACC) and the dorsolateral prefrontal cortex (DLPFC).
Benny Liberg, Christoffer Rahm, Maria Kristoffersen-Wiberg, Mussie Msghina, Peter Aspelin   +4 more
core   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

A prospective series of acute rivaroxaban overdose, coagulopathy and bleeding complications (ATOM 11)

British Journal of Clinical Pharmacology, EarlyView.
Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi, Angela L. Chiew, Keith Harris, Geoffrey K. Isbister   +3 more
wiley   +1 more source

Time Course of Changes in Peripheral Blood Gene Expression During Medication Treatment for Major Depressive Disorder. [PDF]

, 2019
Changes in gene expression (GE) during antidepressant treatment may increase understanding of the action of antidepressant medications and serve as biomarkers of efficacy.
Congdon, Eliza, Cook, Ian A, Coppola, Giovanni, Hamilton, Steven P, Hunter, Aimee M, Krantz, David E, Leuchter, Andrew F   +6 more
core   +1 more source

Melanin-Concentrating Hormone (MCH): Role in REM Sleep and Depression. [PDF]

, 2015
The melanin-concentrating hormone (MCH) is a peptidergic neuromodulator synthesized by neurons of the lateral sector of the posterior hypothalamus and zona incerta.
Benedetto, Luciana, Chase, Michael H, Lagos, Patricia, López-Hill, Ximena, Monti, Jaime M, Pascovich, Claudia, Scorza, Cecilia, Torterolo, Pablo, Urbanavicius, Jessika   +8 more
core   +3 more sources

CYP2C19 Genotype is Associated with Citalopram Treatment Outcomes in a Real‐World Setting

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 metabolizes various selective serotonin reuptake inhibitors (SSRIs) and genetic CYP2C19 variants are associated with SSRI tolerability and response. Yet, whether CYP2C19 variability also impacts citalopram response remained unclear. We here evaluated associations between CYP2C19 genotypes and citalopram prescription data of 11,079 patients from
Yoomi Park, Yitian Zhou, Volker M. Lauschke   +2 more
wiley   +1 more source

Escitalopram facilitates tumor growth and metastasis in rodents: Is it safe?

Neoplasia: An International Journal for Oncology Research
Cancer patients are often treated perioperatively with serotonin reuptake inhibitors (SSRIs) to counteract anxiety and depression. Recent studies suggest that long-term cancer outcomes may also be affected by SSRI use in an agent-dependent manner ...
Yosi Azan, Adam Margalit, Gal Wiener, Elad Sandbank, Ravid Doron, Liat Sorski, Ella Rosenne, Avital Luba Plosky, Avital Gilam, Anabel Eckerling, Noam Shomron, Shamgar Ben-Eliyahu   +11 more
doaj   +1 more source