Results 101 to 110 of about 7,313 (199)

The Resistant Depression Response to Esketamine Assessing Metabolomics (ReDREAM) Project-Untargeted Metabolomics to Identify Biomarkers of Treatment Response to Intranasal Esketamine in Individuals with Treatment-Resistant Depression: A Study Protocol [PDF]

Objective: Treatment-resistant depression (TRD) affects around 20-30% of people with major depressive disorder. In 2019, esketamine nasal spray was approved for TRD by both the US Food and Drug Administration and the European Medicines Agency.
Albert, Umberto, Bartoli, Francesco, Carrà, Giuseppe, Cavaleri, Daniele, Crocamo, Cristina, De Fazio, Pasquale, de Filippis, Renato, Paglia, Giuseppe, Riboldi, Ilaria, Zandonella Callegher, Riccardo   +9 more
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Moving Forward with Ketamine Therapy: Ensuring Safety, Efficacy, and Accessibility in Depression Treatment [PDF]

Ketamine, a medication long used in anesthesia, has emerged as a promising treatment for depression and other mental health disorders. Its rapid onset of action and mechanism, which differs from traditional antidepressants by targeting NMDA receptors ...
DeSanto, Julienne
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Protective effect of esketamine on hepatic ischemia-reperfusion injury

Zhongguo linchuang yanjiu
Esketamine, as a perioperative sedative and analgesic drug, has been widely used in Europe and America. However, the protective effect of esketamine on the liver during the perioperative period is still in the applicated research stage.
DU Shuyao, LYU Jing, ZHOU Ziyu, FENG Guangwu, LUO Xianghong
doaj   +1 more source

Does Esketamine in Cesarean Delivery Increase Postoperative Adversities and Related Diseases? [PDF]

Esketamine has emerged as a promising treatment option, particularly noted for its effectiveness in reducing postpartum depression, alleviating pain, and promoting faster recovery.
Coombs, Kylon, Daniel, Cheryce
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The efficacy and safety of patient-controlled intravenous analgesia with esketamine after total hip arthroplasty: a randomized controlled trial

BMC Anesthesiology
Purpose To evaluate the efficacy and safety of esketamine-based patient-controlled intravenous analgesia following total hip arthroplasty. Methods A total of 135 total hip arthroplasty patients were randomly assigned to one of the three treatment groups:
Song Qu, Wen-Jie Zhang, Hai-Jiao Zhou, Fei Deng, Rui-Juan Liu, Wen-Jun Yan   +5 more
doaj   +1 more source

Exploring the Comorbidity, Pathophysiology, and Integrated Treatment Strategies of Hypertension and Depression [PDF]

Hypertension and depression are widely prevalent conditions with substantial comorbidity. Hypertension, characterized by persistently elevated arterial pressure, is associated with significant cardiovascular morbidity and mortality.
Adadzi, Jerome, Azi, Cornelius I., Carsrud, N.D. Victor, Flores, John V., Holets, Hilary M., Jomsky, Breanna M., Kerna, Nicholas A., Khan, Maria, Ngwu, Dabeluchi C., Pruitt, Kevin D., Saini, Sawanjit, Taha, Wail Taha Mohammed, Zhao, Xuan   +12 more
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Perioperative use of esketamine for the prevention of postpartum depression after cesarean section: a meta-analysis

BMC Pregnancy and Childbirth
Summary Background Esketamine has a relatively low adverse effect on mothers and infants during cesarean sections, making it an ideal adjunct in spinal anesthesia.
Yanhong Li, Kuangyu Zhao, Peipei Cao, Qian Wang, Kairui Li, Jun Zhou   +5 more
doaj   +1 more source

Comparison of the effects of esketamine/midazolam and remifentanil/midazolam on respiratory mechanics in mechanically ventilated patients with acute respiratory distress syndrome

BMC Anesthesiology
Background Esketamine exerts analgesic effects and has pharmacological properties of bronchodilation and elevation of mean arterial pressure, making it an interesting analgesic agent for patients with ARDS. Therefore, we conducted a randomized controlled
Dujuan Qiao, Wei Liu, Huanjia Xue, Rui Liu, Ya Gao, Jingzhi Dong, Wei Wu, Junkai Feng, Min Li, Linong Yao   +9 more
doaj   +1 more source

Comparison of Esketamine/Propofol and Sufentanil/Propofol on Intraoperative Hypoxemia During Bronchoscopy: A Randomized Trial

Drug Design, Development and Therapy
Xiao Huang,1 Xueyang Li,1 Yuan Sun,2 Anshi Wu,1 Pan Ai1 1Department of Anesthesiology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Department of Pharmacy, Peking University Third Hospital, Beijing, People’
Huang X, Li X, Sun Y, Wu A, Ai P
doaj  

Towards personalized management of complex regional pain syndrome [PDF]

This dissertation illustrates how the management of CRPS should be personalized. Patients with CRPS suffer continuous pain and can experience sensory, vasomotor, sudomotor, motor and trophic symptoms in the affected extremity.
Mangnus, Tom
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