Results 101 to 110 of about 7,663 (213)

Exploring the Comorbidity, Pathophysiology, and Integrated Treatment Strategies of Hypertension and Depression [PDF]

Hypertension and depression are widely prevalent conditions with substantial comorbidity. Hypertension, characterized by persistently elevated arterial pressure, is associated with significant cardiovascular morbidity and mortality.
Adadzi, Jerome, Azi, Cornelius I., Carsrud, N.D. Victor, Flores, John V., Holets, Hilary M., Jomsky, Breanna M., Kerna, Nicholas A., Khan, Maria, Ngwu, Dabeluchi C., Pruitt, Kevin D., Saini, Sawanjit, Taha, Wail Taha Mohammed, Zhao, Xuan   +12 more
core   +2 more sources

The perspectives of patients with depression toward esketamine, and the influence of their medication adherence on their viewpoints: a Saudi cross-sectional study

Frontiers in Psychiatry
BackgroundNasal esketamine has demonstrated efficacy in the management of treatment-resistant depression and psychiatric emergency due to major depression.
Ahmad H. Almadani, Ahmad H. Almadani, Ayedh H. Alghamdi, Ayedh H. Alghamdi, Fahad B. Alfahad, Abdullah S. Alibrahim, Abdulrahman I. Binbakhit, Ziyad B. Alenazi, Lama M. Alruwaili, Abdulrahman A. Alshahwan, Abdullah K. Muhnna, Mohammed A. Aljaffer, Mohammed A. Aljaffer   +12 more
doaj   +1 more source

Comparison of R-ketamine and rapastinel antidepressant effects in the social defeat stress model of depression [PDF]

, 2016
Bangkun Yang, Chun Yang, Ji-chun Zhang, Kenji Hashimoto, Mei Han, Min Ma, Qian Ren, Qian-Xue Chen, Wei Yao   +8 more
core   +1 more source

Effects of esketamine–sufentanil for patient-controlled intravenous analgesia in women following cesarean section: A randomized clinical trial

Frontiers in Pharmacology
BackgroundPostoperative pain following cesarean section can cause maternal anxiety, limited ambulation, and even postpartum depression. In this study, we aimed to investigate the effects of esketamine for postoperative patient-controlled intravenous ...
Yanping Zhao, Lin Liu, Yi Hou, Jiaming Fan   +3 more
doaj   +1 more source

Oral esketamine in patients with treatment-resistant depression:a double-blind, randomized, placebo-controlled trial with open-label extension [PDF]

About one-third of patients with depression do not achieve adequate response to current treatment options. Although intravenous and intranasal administrations of (es)ketamine have shown antidepressant properties, their accessibility and scalability are ...
aan het Rot, Marije, Kamphuis, Jeanine, Schoevers, Robert A, Smith-Apeldoorn, Sanne Y, Spijker, Jan, van Asselt, Antoinette D I, van der Meij, Annemarie, Veraart, Jolien K E   +7 more
core   +1 more source

Improvements in health-related quality of life with esketamine nasal spray versus quetiapine extended release [PDF]

Background: Clinical response and remission may not fully reflect patient priorities in treatment resistant depression (TRD); health-related quality of life (HRQoL) outcomes should be assessed to comprehensively capture treatment benefits.
Baune, Bernhard T., Buyze, Jozefien, Cleare, Anthony J., Johnson, Shaun, Kambarov, Yerkebulan, Olisa, Nigel, Reif, Andreas, Schuster, Falk, Vieta, Eduard, von Holt, Christian, Werner-Kiechle, Tamara   +10 more
core   +1 more source

The efficacy and safety of patient-controlled intravenous analgesia with esketamine after total hip arthroplasty: a randomized controlled trial

BMC Anesthesiology
Purpose To evaluate the efficacy and safety of esketamine-based patient-controlled intravenous analgesia following total hip arthroplasty. Methods A total of 135 total hip arthroplasty patients were randomly assigned to one of the three treatment groups:
Song Qu, Wen-Jie Zhang, Hai-Jiao Zhou, Fei Deng, Rui-Juan Liu, Wen-Jun Yan   +5 more
doaj   +1 more source

Efficacy and safety of ketamine and esketamine in reducing the incidence of postpartum depression: an updated systematic review and meta-analysis

BMC Pregnancy and Childbirth
Background Postpartum depression (PPD) is categorized by the Disorders-Fifth Edition as depression that begins during pregnancy or within the first month after giving birth. Ketamine and esketamine have shown promising results in the treatment of several
Moaz Yasser Darwish, Abdallah A. Helal, Yousif Ahmed Othman, Manar Alaa Mabrouk, Aya Alrawi, Taha Abd-ElSalam Ashraf, Nada K. Abdelsattar, Fatma Mohammed Sayed, Mohamed Abd-ElGawad   +8 more
doaj   +1 more source

Perioperative use of esketamine for the prevention of postpartum depression after cesarean section: a meta-analysis

BMC Pregnancy and Childbirth
Summary Background Esketamine has a relatively low adverse effect on mothers and infants during cesarean sections, making it an ideal adjunct in spinal anesthesia.
Yanhong Li, Kuangyu Zhao, Peipei Cao, Qian Wang, Kairui Li, Jun Zhou   +5 more
doaj   +1 more source

Ketamine in the Treatment of Depression [PDF]

Introduction Depression is one of the most common mental illnesses. Over the course of a lifetime, several percent of the adult population suffers from depression.
Cioch, Michał Jakub, Doman , Katarzyna, Hermanowicz, Kamil, Kaczmarska, Urszula Agnieszka, Komada, Dawid, Mycyk, Marcin, Najdek , Agnieszka, Nowak, Julia, Oleksy , Daria, Woźniak, Aleksandra   +9 more
core   +1 more source