Results 11 to 20 of about 111,421 (336)

Chemoprevention of esophageal adenocarcinoma

Gastroenterology Report, 2020
Abstract Esophageal adenocarcinoma (EAC) is a major cause of cancer-related death, particularly in Western populations, and is rapidly rising in Asian populations at this time. Virtually all EACs develop from the precursor lesion Barrett’s esophagus (BE), which is the most significant risk factor for EAC.
John M. Inadomi, Erik J. Snider, William M. Grady, William M. Grady, Andrew M. Kaz   +4 more
openaire   +3 more sources

Hereditary Factors in Esophageal Adenocarcinoma [PDF]

Gastrointestinal Tumors, 2014
<b><i>Background:</i></b> The vast majority of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC) cases are sporadic and caused by somatic mutations. However, over the last decades several families have been identified with clustering of EAC.
Bas P. L. Wijnhoven, Anja Wagner, J. Jan B. van Lanschot, Anna M. J. van Nistelrooij, Winand N.M. Dinjens, Manon C.W. Spaander   +5 more
openaire   +4 more sources

Metabolomics study of esophageal adenocarcinoma [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2011
The objective of this study was to detect and evaluate reliable metabolite markers for screening and monitoring treatment of patients with esophageal adenocarcinoma (EAC) by studying metabolomics. The sensitivity and specificity of the study were evaluated not only for EAC but also for Barrett esophagus and high-grade dysplasia, which are widely ...
Zane Hammoud, Jian Zhang, Lingyan Liu, Daniel Raftery, Siwei Wei, G. A. Nagana Gowda, Kenneth A. Kesler   +6 more
openaire   +3 more sources

Oral Bisphosphonate Exposure and the Risk of Upper Gastrointestinal Cancers. [PDF]

PLoS ONE, 2015
The association between oral bisphosphonate use and upper gastrointestinal cancer has been controversial. Therefore, we examined the association with esophageal and gastric cancer within the Kaiser Permanente, Northern California population. A total of 1,
Emily Vogtmann, Douglas A Corley, Lucy M Almers, Chris R Cardwell, Liam J Murray, Christian C Abnet   +5 more
doaj   +1 more source

Dedifferentiation of esophageal progenitors in metaplasia and cancer

Molecular & Cellular Oncology, 2021
Barrett syndrome is a squamo-columnar metaplasia increasing the risk of developing esophageal adenocarcinoma. Recently, we showed that esophageal cells can transdifferentiate into undifferentiated columnar cells in vivo.
Alizée Vercauteren Drubbel, Benjamin Beck   +1 more
doaj   +1 more source

Treatment utilization and outcomes in elderly patients with locally advanced esophageal carcinoma: A review of the National Cancer Database [PDF]

, 2017
For elderly patients with locally advanced esophageal cancer, therapeutic approaches and outcomes in a modern cohort are not well characterized. Patients ≥70 years old with clinical stage II and III esophageal cancer diagnosed between 1998 and 2012 were ...
Bradley, Jeffrey D, Kozower, Benjamin, Lockhart, A. Craig, Meyers, Bryan F, Parikh, Parag J, Perkins, Stephanie M, Puri, Varun, Roach, Michael C, Robinson, Cliff G, Samson, Pamela P, Vlacich, Gregory   +10 more
core   +2 more sources

Recurrence following anastomotic leakage after surgery for carcinoma of the distal esophagus and gastroesophageal junction. a systematic review [PDF]

, 2019
BACKGROUND: Esophageal cancer is the ninth most common cancer. The only potentially curative treatment is surgical resection, which unfortunately is still associated with major complications, the most important being anastomotic leakage, currently with ...
Antolino, Laura, Aurello, Paolo, Berardi, Giammauro, Cinquepalmi, Matteo, D'Angelo, Francesco, GIOVANNI RAMACCIATO, And, Moschetta, Giovanni, Nigri, Giuseppe, Valabrega, Stefano   +8 more
core   +1 more source

Current status and future perspectives on the etiology of esophageal adenocarcinoma

Frontiers in Oncology, 2012
Esophageal adenocarcinoma is the most common type of esophageal cancer in most Western countries and is an important contributor to overall cancer mortality.
Aaron P. Thrift, Aaron P. Thrift, Nirmala ePandeya, David C. Whiteman   +3 more
doaj   +1 more source

CA19-9-producing esophageal adenocarcinoma originating from the esophageal cardia of the mid-thoracic esophagus: a case report

Surgical Case Reports, 2021
Background Although there are many studies on primary esophageal adenocarcinoma arising from Barrett's esophagus or ectopic gastric mucosa, reports on adenocarcinoma arising from esophageal cardiac glands are extremely rare.
Naoki Kuwayama, Isamu Hoshino, Hisashi Gunji, Takeshi Kurosaki, Toru Tonooka, Hiroaki Soda, Itaru Sonoda, Ryotaro Eto, Nobuhiro Takiguchi, Yoshihiro Nabeya, Makiko Itami, Wataru Takayama   +11 more
doaj   +1 more source

Human Microbiota in Esophageal Adenocarcinoma: Pathogenesis, Diagnosis, Prognosis and Therapeutic Implications

Frontiers in Microbiology, 2022
Esophageal adenocarcinoma (EAC) is one of the main subtypes of esophageal cancer. The incidence rate of EAC increased progressively while the 5-year relative survival rates were poor in the past two decades.
Wanyue Dan, Wanyue Dan, Lihua Peng, Bin Yan, Zhengpeng Li, Fei Pan   +5 more
doaj   +1 more source