Results 61 to 70 of about 115,341 (318)

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice

BMC Gastroenterology, 2009
Background Esophago-gastroduodenal anastomosis with rats mimics the development of human Barrett's esophagus and esophageal adenocarcinoma by introducing mixed reflux of gastric and duodenal contents into the esophagus. However, use of this rat model for
Chen Xiaoxin, Yang Chung S, Liu Ba, Hao Jing   +3 more
doaj   +1 more source

Deoxycholic Acid Upregulates the Reprogramming Factors KFL4 and OCT4 Through the IL-6/STAT3 Pathway in Esophageal Adenocarcinoma Cells

Technology in Cancer Research & Treatment, 2020
Cancer stem cells, a special subgroup of cancer cells, have self-renewal capabilities and multidirectional potential, which may be reprogrammed from the dedifferentiation of cancer cells, contributing to the failure of clinical treatments.
Mei Chen BSc, AXiaojun Ye MSc, Jingxi Wei BSc, Ruihua Wang MD, Karen Poon PhD   +4 more
doaj   +1 more source

A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β

Advanced Science, EarlyView.
This study demonstrates that the expression of A20, a ubiquitin‐editing enzyme, is positively correlated with oxaliplatin sensitivity in colorectal cancer (CRC). Mechanistically, A20 enhances oxaliplatin sensitivity by inhibiting NF‐κB nuclear translocation through monoubiquitination of IKK‐β.
Fan Luo, Ting Yang, Jiaxin Cao, Qun Chen, Zhenhai Lu, Feiteng Lu, Chaozhuo Lin, Zengfei Xia, Yuanzhong Yang, Peng Li, Wenjuan Ma, Min Luo, Rongxin Zhang   +12 more
wiley   +1 more source

Modeling of influential predictors of gastric cancer incidence rates in Golestan Province, North Iran [PDF]

, 2014
Golestan province has a reputation for relatively high incidence rates of gastric cancer in Iran. Along with dietary, lifestyle and environmental influential factors, soil selenium and high levels of pesticide used may exert influence in this region. The
Behnampour, N., Hajizadeh, E., Semnani, S., Zayeri, F.   +3 more
core   +1 more source

Esophageal Adenocarcinoma Metastatic to the Choroid with Extrascleral Extension [PDF]

, 2023
Haley S. D’Souza, Lauren A. Dalvin, Lilly H. Wagner   +2 more
openalex   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Expression, localization and polymorphisms of the nuclear receptor PXR in Barrett's esophagus and esophageal adenocarcinoma

BMC Gastroenterology, 2011
Background The continuous exposure of esophageal epithelium to refluxate may induce ectopic expression of bile-responsive genes and contribute to the development of Barrett's esophagus (BE) and esophageal adenocarcinoma.
Kusters Johannes G, Siersema Peter D, van Dekken Herman, Pot Raymond GJ, Moons Leon MG, Capello Astrid, Menke Vivianda, van de Winkel Anouk, van der Laan Luc JW, Kuipers Ernst J   +9 more
doaj   +1 more source

Area-level attributes and esophageal adenocarcinoma in surveillance, epidemiology and end results registries. [PDF]

PLoS ONE, 2013
PURPOSE: To examine the associations between area-level socioeconomic attributes and stage of esophageal adenocarcinoma diagnoses in 16 SEER cancer registries during 2000-2007.
Armen A Ghazarian, Megan A Murphy, Maria R Khan, Brit I Saksvig, Sean F Altekruse   +4 more
doaj   +1 more source

Dietary phytoestrogens and esophageal cancer [PDF]

, 2013
Esophageal cancer is the eighth most common invasive cancer in the world, a cancer with an increasing incidence and male predominance, and there is a great need for potential dietary prevention.
Lin, Yulan
core   +1 more source