In a nationwide multicenter cohort, an early response to tolvaptan (≥ 1.5‐kg weight loss within 7 days) was independently associated with improved long‐term survival in patients with cirrhosis and hepatic edema. Early initiation before renal impairment or hyponatremia may optimize treatment response and prognosis. ABSTRACT Aim Hepatic edema indicates a
Kaori Koyano +22 more
wiley +1 more source
Radiomics and prognostic nutritional index for predicting postoperative survival in esophageal carcinoma. [PDF]
Luo W +7 more
europepmc +1 more source
Precision medicine in cutaneous melanoma—A comprehensive review
Precision medicine tailors treatment to each patient, beginning with detailed diagnostics. In melanoma, it has advanced considerably: Some methods are in practice and guidelines, while others are commercially available but not routine. This review highlights current and emerging approaches, including molecular profiling, imaging, biomarkers and AI ...
Markus Reitmajer, Lukas Flatz
wiley +1 more source
Development and validation of a multivariate predictive model for cancer-related fatigue in esophageal carcinoma: a prospective cohort study integrating biomarkers and psychosocial factors. [PDF]
Lan Y +6 more
europepmc +1 more source
ABSTRACT Background Radiotherapy‐induced malignancies are well‐documented, but the clinicopathological profile and prognostic factors of radiation‐induced oral squamous cell carcinoma (R‐OSCC) remain unclear. Methods The present review was conducted in accordance with the PRISMA guidelines and has been registered in the PROSPERO (registration number ...
Anne Evelyn Oliveira Moura +9 more
wiley +1 more source
Metastatic Pulmonary Calcification with the Coexistence of known Esophageal Carcinoma: Case Report and Literature Review. [PDF]
Bhinder KK, Sayeed S, Kanwal A, Khan N.
europepmc +1 more source
The Leuven Consensus provides a classification scheme for the diagnosis of pharyngeal and upper esophageal sphincter (UES) motor disorders using metrics derived from pharyngeal high‐resolution manometry‐impedance (P‐HRM‐I). These recommendations complement routine instrumental investigations and provide a standardized process, criteria, and ...
Taher I. Omari +25 more
wiley +1 more source
Identification of potential drug targets and possible drugs for esophageal carcinoma from genetic insights: a comprehensive two-sample Mendelian randomization study. [PDF]
Wang J +7 more
europepmc +1 more source
USP10 in Neurological Disorders: Mechanistic Insights and Emerging Therapeutic Strategies
USP10 is a deubiquitinating enzyme that affects neurological diseases through multiple mechanisms, including the accumulation of toxic proteins, autophagy, and immune responses. In this review, we discuss the structure and characteristics of USP10 and summarize the role of USP10 in neurological disorders.
Celemuge +5 more
wiley +1 more source
The prognostic significance of FMR1 expression and its immunomodulatory implications in esophageal carcinoma. [PDF]
Tang Q +8 more
europepmc +1 more source

