Results 61 to 70 of about 210,346 (221)

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Retrospective Insights: Unveiling the Sociodemographic Tapestry of Esophageal Carcinoma in Northeast India from a Cancer Center’s Records Analysis

Forum of Clinical Oncology
This study delves into esophageal carcinoma in Northeast India, spotlighting Assam due to the state showing heightened prevalence of esophageal carcinoma.
Shiva Divya
doaj   +1 more source

Prognostic relevance of Centromere protein H expression in esophageal carcinoma

BMC Cancer, 2008
Background Many kinetochore proteins have been shown to be associated with human cancers. The aim of the present study was to clarify the expression of Centromere protein H (CENP-H), one of the fundamental components of the human active kinetochore, in ...
Guo Xian-Zhi, Zhang Ge, Wang Jun-Ye, Liu Wan-Li, Wang Fang, Dong Ju-Qin, Xu Li-Hua, Cao Jing-Yan, Song Li-Bing, Zeng Mu-Sheng   +9 more
doaj   +1 more source

Recurrence of intestinal metaplasia and early neoplasia after endoscopic eradication therapy for Barrett’s esophagus: A systematic review and meta-analysis [PDF]

, 2017
Background Conflicting data exist with regard to recurrence rates of intestinal metaplasia (IM) and dysplasia after achieving complete eradication of intestinal metaplasia (CE-IM) in Barrett’s esophagus (BE) patients.
Cinnor, Birtukan, Das, Ananya, Early, Dayna S, Edmundowicz, Steven A, Fujii-Lau, Larissa L, Gaddam, Srinivas, Komanduri, Srinadh, Kushnir, Vladimir, Mullady, Daniel, Muthusamy, V. Raman, Shaheen, Nicholas, Simon, Violette C, Wani, Sachin, Wilson, Robert   +13 more
core   +2 more sources

Highly Active Cu14 Cluster Precisely Activates Autophagy Inhibitor to Amplify Cuproptosis Immunotherapy

Advanced Science, EarlyView.
An atomically precise Cu14 cluster‐mediated bond scission reaction pioneers the amplification of the antitumor immune response via synergetic cuproptosis‐associated immunogenic cell death induction and in situ autophagy blockade. ABSTRACT Transition metal‐mediated cleavage mechanisms have emerged as an effective means to mitigate the off‐target ...
Qiu‐Xu Zang, Wei‐Tong Chen, Yu‐Ying Shen, Zhao‐Yang Wang, Kai Li, Xueli Zhao, Yanjuan Sang, Xiaoyuan Chen, Shuang‐Quan Zang   +8 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Overexpressed PTOV1 associates with tumorigenesis and progression of esophageal squamous cell carcinoma

Tumor Biology, 2017
PTOV1 has been demonstrated to play an extensive role in many types of cancers. This study takes the first step to clarify the potential relationship between esophageal squamous cell carcinoma and PTOV1 expression and highlight the link between PTOV1 and
Rong Li, Ai-min Leng, Xiao-ming Liu, Ting-zi Hu, Lin-fang Zhang, Ming Li, Xiao-xia Jiang, Yan-wu Zhou, Can-xia Xu   +8 more
doaj   +1 more source

Involvement of CXCR4 chemokine receptor in metastastic HER2-positive esophageal cancer.

PLoS ONE, 2012
A functional linkage of the structurally unrelated receptors HER2 and CXCR4 has been suggested for breast cancer but has not been evaluated for esophageal carcinoma. The inhibition of HER2 leads to a reduction of primary tumor growth and metastases in an
Stephanie J Gros, Nina Kurschat, Astrid Drenckhan, Thorsten Dohrmann, Evelyn Forberich, Katharina Effenberger, Uta Reichelt, Robert M Hoffman, Klaus Pantel, Jussuf T Kaifi, Jakob R Izbicki   +10 more
doaj   +1 more source

Authentication of newly established human esophageal squamous cell carcinoma cell line (YM-1) using short tandem repeat (STR) profiling method [PDF]

, 2016
Cross-contamination during or early after establishment of a new cell line could result in the worldwide spread of a misidentified cell line. Therefore, newly established cell lines need to be authenticated by a reference standard method.
Ayyoob, K., Jahanbakhsh, A., Masoud, K., Vahideh, K.   +3 more
core  

Esophageal Neuroendocrine Carcinoma With Focal Squamous Cell Carcinoma Component

Journal of Investigative Medicine High Impact Case Reports, 2020
This study was about a 70-year-old man with progressive dysphagia. Esophagogastroduodenoscopy showed a 1.2-cm circumferential ulcerative mass at the level of 23 cm from the upper incisors in the upper esophagus.
Min Kyun Kang, Do Kyun Kang
doaj   +1 more source