Results 61 to 70 of about 126,956 (339)

Therapeutic approaches to gastroesophageal junction adenocarcinomas [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108681/1/nyas12532 ...
Agrawal, Aloia, Apisarnthanarax, Ayyappan, Baardwijk, Bang, Barbour, Bettstetter, Blom, Bogush, Bogush, Bruzzi, Brücher, Brücher, Brücher, Brücher, Cerfolio, Chang, Chirieac, Cunningham, Dikken, Dulak, Eto, Farris, Gonzalez, Griffin, Gurland, Hagen, Heijl, Heijl, Illig, Kwee, Lambrecht, Langer, Langer, Loon, Mandard, Mann, Marsman, Medical Research Council Oesophageal Cancer Working Group, Miller, Moertel, Peyre, Peyre, Ronellenfitsch, Rossum, Sarkaria, Schneider, Shapiro, Siewert, Sjoquist, Smit, Stahl, Swisher, Swisher, Takebayashi, Tepper, Therasse, Walsh, Westerterp, Xie   +60 more
core   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Point mutations of the P53 gene, human hepatocellular carcinoma and aflatoxins [PDF]

, 1993
The tumor suppressor p53 exerts important protective functions towards DNA-damaging agents. Its inactivation by allelic deletions or point mutations within the P53 gene as well as complex formation of wildtype p53 with cellular or viral proteins is a ...
Alexander L. Gerbes, Aoyama, Barak, Bressac, Bressac, Buetow, Caselmann, Challen, Colombo, Donehower, Fields, Finlay, Foster, Halevy, Hsu, Jenkins, Kastan, Kekulé, Kew, Kress, Lane, Laurent-Puig, Lilleberg, Livingstone, Ludlow, Malkin, Marshall, Meyer, Meyer, Mueller, Murakami, Nigro, Ozturk, Raycroft, Sarnow, Slagle, Srivastava, Sturzbecher, Taylor, Wolfgang H. Caselmann, Wollersheim   +40 more
core   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

Molecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo, Carlos M. Martínez‐Cáceres, Manuel Bernabé‐García, Vicente Munitiz, David Ruiz de Angulo, Pascual Parrilla, Ángeles Ortiz, Luisa F. Martínez de Haro, María L. Cayuela   +8 more
wiley   +1 more source

Correlation between sarcopenia and esophageal cancer: a narrative review

World Journal of Surgical Oncology
Background In recent years, the research on the relationship between sarcopenia before and after the treatment of esophageal cancer, as well as its impact on prognosis of esophageal cancer, has increased rapidly, which has aroused people’s attention to ...
Shenglan Li, Kaiqiang Xie, Xiaoxiong Xiao, Pingsheng Xu, Mimi Tang, Dai Li   +5 more
doaj   +1 more source

Respiratory muscle strength of patients with esophagus and stomach neoplasms

Fisioterapia em Movimento
Introduction: In cancer patients, the reduced food intake causes weight loss and promotes protein-calorie malnutrition. This results in loss of lean body mass, which affects both skeletal muscles and respiratory muscles.
Evelyn Aline Boscolo Ruivo, Juliana Rodrigues Correia Mello, Odete Mauad Cavenaghi, Alexandre Lins Werneck, Lucas Lima Ferreira   +4 more
doaj   +1 more source

Giant Esophageal Lipoma as an Uncommon Cause of Diverticula

Case Reports in Gastroenterology, 2016
Esophageal lipoma is an uncommon benign tumor of the esophagus and accounts for only 0.4% of all benign neoplasms of the gastrointestinal system. The majority of these are located in the cervical part; only very few are located in the lower third of the ...
Erdal Yekeler, Alkin Yazicioglu, Mahmut Subasi, Hacer Boztepe   +3 more
doaj   +1 more source

Angiogenesis and Mast Cells Density in Oral and Esophageal Squamous Cell Carcinomas

Acta Medica Iranica, 2020
Despite the similarities between oral and esophageal squamous cell carcinomas (SCCs), the survival rate of this cancer is relatively low in the esophagus compared to the oral cavity.
Sadra Masali, Rosa Miri, Mojgan Alaeddini, Shahroo Etemad-Moghadam, Donia Sadri, Fatemeh Shahsavari   +5 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source