Results 161 to 170 of about 102,250 (298)

Hypervision Proton Surgery: The Future Direction of Proton Therapy

iNew Medicine, EarlyView.
ABSTRACT Proton beams provide unique physical advantages characterized by a low entrance dose, negligible exit dose, and a sharp Bragg peak, which enable superior sparing of normal tissues and support safe dose escalation for improved tumor control. However, conventional photon‐based fractionation remains widely used in proton therapy, where prolonged ...
Li Li, Shuanghu Yuan
wiley   +1 more source

The P0.1 maneuver as an alternative method for assessing the validity of esophageal pressure measurements during assisted ventilation: an exploratory analysis. [PDF]

Intensive Care Med Exp
Bastian TM, Eimer C, Behmüller F, Weiler N, Bellani G, Schädler D, Becher T.   +6 more
europepmc   +1 more source

The Role of Endothelin‐1 in Autoimmune Diseases: Mechanistic Insights and Therapeutic Targets

iNew Medicine, EarlyView.
The Role of Endothelin‐1 in Autoimmune Diseases. NF‐κB: nuclear factor kappa‐B; MAPK: mitogen‐activated protein kinase; PI3K: phosphoinositide 3‐kinase; ROS: reactive oxygen species; CTGF: connective tissue growth factor; TGF‐β: transforming growth factor‐β.
Xun Gong, Zhenyu Wang, Suyin Yang, Kaige Gao, Xin Yang, Min Tang   +5 more
wiley   +1 more source

Erroneous calibration of esophageal pressure in case of airway closure. [PDF]

Crit Care
Docci M, Beloncle F, Lesimple A, Piraino T, Raimondi Cominesi D, Restivo A, Sousa MLA, Rezoagli E, Mercat A, Richard JC, CAVIAR Group, Brochard L.   +11 more
europepmc   +1 more source

Transpulmonary driving pressure, without esophageal pressure measurements, instead of airway driving pressure. [PDF]

Intensive Care Med, 2020
Stenqvist O.
europepmc   +1 more source

Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone. [PDF]

, 2016
Rattan, Satish
core   +2 more sources

SUMOylation regulates tumorigenesis and progression: Molecular mechanisms and therapeutic applications

Interdisciplinary Medicine, EarlyView.
SUMOylation, a dynamic post‐translational modification, acts as a master regulator at the heart of tumor malignancy. Our work delineates how the SUMOylation cycle—mediated by E1/E2/E3 enzymes and reversed by SENPs—orchestrates multiple hallmarks of cancer. The central pathway converges on three critical pathological axes: 1.
Yimao Wu, Zichang Chen, Yinting Hu, Gokhan Zengin, Qian Zhang, Meng‐Yao Li, Wenlong Sun   +6 more
wiley   +1 more source

Individualized Lung-Protective Ventilation Strategy Based on Esophageal Pressure Monitoring in Patients With ARDS Associated With Severe Acute Pancreatitis-A Randomized Controlled Trial. [PDF]

World J Surg
Zhao Y, Zhang S, Liu C, Wang X.
europepmc   +1 more source

Relative Contributions of Gastrointestinal‐Specific Hypervigilance and Anxiety in Explaining Eating Disorder Symptoms

Journal of Clinical Psychology, EarlyView.
ABSTRACT Objective Gastrointestinal (GI) disturbances and eating disorder symptoms commonly co‐occur. Hypervigilance and anxiety about GI symptoms may motivate eating disorder behaviors to manage and/or avoid GI symptoms. We hypothesized that GI‐specific anxiety would be more strongly associated with dietary restriction and purging than GI‐specific ...
Gabriella Pucci, Naomi G. Hill, Zoe Schneider, Tiffany A. Brown, Helen Burton‐Murray, Livia Guadagnoli, K. Jean Forney   +6 more
wiley   +1 more source

A Singular Spectrum Analysis-Based Data-Driven Technique for the Removal of Cardiogenic Oscillations in Esophageal Pressure Signals. [PDF]

IEEE J Transl Eng Health Med, 2020
Mukhopadhyay SK, Zara M, Telias I, Chen L, Coudroy R, Yoshida T, Brochard L, Krishnan S.   +7 more
europepmc   +1 more source