What Is Your Diagnosis? Fine‐Needle Aspirate From a Lingual Mass in a Cat
Veterinary Clinical Pathology, EarlyView.
Emma Stacey +3 more
wiley +1 more source
Mesothelin as Biomarker and Therapeutic Target for Immunotherapy in Cancer
Mesothelin overexpression activate important pathways like nuclear factor k‐light‐chain‐enhancer of activated B cells (NF‐κB) and interleukin‐6 (IL‐6). This in turn causes numerous cancers, such as pancreatic and ovarian cancers. MSLN‐targeting immunotherapies, like monoclonal antibodies, have shown efficacy.
Manoj Kumar Gupta +2 more
wiley +1 more source
PVR Mediates Resistance to IL21.CD276.CAR-T Therapy in Esophageal Squamous Cell Carcinoma. [PDF]
Wang L +10 more
europepmc +1 more source
Cytoskeletal Dynamics in Cancer: From Pathogenesis to Treatment
This review systematically addresses the fundamental roles of the cytoskeleton (actin filaments, microtubules, and intermediate filaments) in cancer progression. We focus on how cytoskeletal dynamics regulate tumor proliferation, metastasis, and programmed cell death, while also modulating the immune microenvironment. Understanding these mechanisms may
Jie Chen +9 more
wiley +1 more source
Peripheral Blood Biomarkers for Predicting the Efficacy of Neoadjuvant Immunochemotherapy in Locally Advanced Esophageal Squamous Cell Carcinoma. [PDF]
Shen Y +6 more
europepmc +1 more source
Abstract Uveal melanoma (UM) is a deadly ocular malignancy with well‐described genetic alterations that predict disease outcome. However, our current understanding of the biological underpinnings of high‐risk uveal melanoma progression remains relatively limited. Using RNA expression profiles from 250 patients with UM, we identified 12 novel biomarkers
QCC van den Bosch +7 more
wiley +1 more source
Dynamic survival prediction using longitudinal AGR in unresectable locally advanced esophageal squamous cell carcinoma. [PDF]
Du F, Deng W, Xiao Y, Yu R, Jia J.
europepmc +1 more source
The study identified key barriers to optimal patient‐centered care, including delayed diagnosis due to awareness and stigma‐related barriers among patients and caregivers, and opportunities to enhance multidisciplinary coordination. Resource limitations impacted nursing and psychosocial support, while access to support care varied across regions.
Edwin Pun Hui +10 more
wiley +1 more source
Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach. [PDF]
Lv Y, Jiang Y, Hui K, Jiang X.
europepmc +1 more source
The evolving role of immunotherapy in ovarian cancer
Abstract Ovarian cancer remains a major cause of gynecologic cancer mortality; and, although immune checkpoint inhibitors have transformed treatment in other solid tumors, their activity in ovarian cancer has been limited by tumor heterogeneity, an immunosuppressive tumor microenvironment, and the lack of robust predictive biomarkers.
Ana Carolina Veneziani +2 more
wiley +1 more source

