Results 191 to 200 of about 124,971 (293)

Immunotherapy in advanced gastroesophageal cancers: A meta‐analysis of sex‐based outcomes in overall survival

open access: yesInternational Journal of Cancer, Volume 158, Issue 10, Page 2697-2708, 15 May 2026.
What's New? Immune checkpoint inhibitors (ICIs) improve survival in advanced gastroesophageal cancer (GEC), but their benefits may differ by sex. Little is known, however about the impact of sex‐related immune differences on ICI efficacy. In this meta‐analysis, sex‐specific outcomes of ICI therapy were evaluated in advanced GEC, encompassing both ...
Michael Masetti   +4 more
wiley   +1 more source

Location characteristics of superficial esophageal squamous cell carcinoma. [PDF]

open access: yesSci Rep
Ryu DG   +7 more
europepmc   +1 more source

What Is Your Diagnosis? Fine‐Needle Aspirate From a Lingual Mass in a Cat

open access: yes
Veterinary Clinical Pathology, EarlyView.
Emma Stacey   +3 more
wiley   +1 more source

Synergistic Effects of DNA‐PKcs Inhibition and Radiotherapy in Esophageal Squamous Cell Carcinoma

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Radiotherapy induces double‐strand DNA breaks in esophageal squamous cell carcinoma, triggering DNA‐PKcs phosphorylation and activating the non‐homologous end joining (NHEJ) repair pathway, which contributes to radioresistance. Inhibiting DNA‐PKcs disrupts this repair mechanism, enhancing radiosensitivity by blocking NHEJ, amplifying DNA damage, and ...
Jiekun Qian   +9 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, Volume 16, Issue 5, Page 979-999, May 2026.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Metformin Use and Development of Esophageal Squamous Cell Carcinoma.

open access: yesJAMA Netw Open
Xie SH   +6 more
europepmc   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, Volume 16, Issue 5, Page 921-931, May 2026.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

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