The Natural Flavonoid Pectolinarigenin Targets On-Canonical NF-κB Pathway to Inhibit Esophageal Squamous Cell Carcinoma and Enhances Paclitaxel Efficacy. [PDF]
Li E +7 more
europepmc +1 more source
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya +2 more
wiley +1 more source
miR-335-3p acts as a tumor suppressor in esophageal squamous cell carcinoma and predicts favorable prognosis. [PDF]
He M, Lu S, Yang F, Xu J, Zhu R.
europepmc +1 more source
Although neoadjuvant chemotherapy with fluorouracil, cisplatin, and docetaxel (NAC‐DCF) is the current standard neoadjuvant regimen for esophageal squamous cell carcinoma, its substantial toxicity underscores the need to identify patients who derive the greatest benefit.
Eiji Higaki +9 more
wiley +1 more source
Applications of Artificial Intelligence in the Endoscopic Detection and Characterization of Early Esophageal Squamous Cell Carcinoma: A Scoping Review. [PDF]
Rodríguez-Velásquez F +5 more
europepmc +1 more source
This study evaluated immune‐related biomarkers in esophageal squamous cell carcinoma treated with immune checkpoint inhibitors after postoperative recurrence. PD‐L1 expression in tumor‐associated macrophages and tumor cells, together with HLA class I downregulation and HLA‐DR expression, were associated with favorable responses to immunotherapy.
Kosuke Kanemitsu +9 more
wiley +1 more source
Metformin Use and Development of Esophageal Squamous Cell Carcinoma.
Xie SH +6 more
europepmc +1 more source
Sequential multimodal endoscopic therapy for recurrent extensive superficial basaloid esophageal squamous cell carcinoma with a 24-month follow-up. [PDF]
Huang J, Wu W, Zhang X, Chang Y.
europepmc +1 more source
This meta‐analysis of 208 cases shows that salvage esophagectomy for cT4 esophageal squamous cell carcinoma achieves a 72% R0 resection rate, offering a curative pathway for selected patients. However, it remains a high‐risk procedure with an 18% anastomotic leak rate and 30% major complications (Clavien–Dindo ≥ III).
Makoto Sakai +4 more
wiley +1 more source
Prognostic value and potential upstream regulator of Schwann cells in esophageal squamous cell carcinoma. [PDF]
Lei Y +9 more
europepmc +1 more source

