Results 211 to 220 of about 337,805 (303)

Applications of artificial intelligence in postoperative surveillance and management of esophageal squamous cell carcinoma. [PDF]

Front Artif Intell
Li K, Qian Z, Mao J, Lu S, Zhang J, Han Y, Leng X.   +6 more
europepmc   +1 more source

Cyclins and Cyclin‐Dependent Kinases: Structure, Biological Functions, and Innovative Targeting Strategies in Cancer

MedComm, Volume 7, Issue 9, September 2026.
This work synthesizes recent insights into the pathological roles of cyclins and cyclin‐dependent kinases (CDKs) across human cancers, highlights state‐of‐the‐art innovative approaches (especially targeted degradation and redistribution of CDK/cyclin proteins) for cancer therapy, and outlines future directions for CDK/cyclin‐related biomedical research.
Suya Zheng, Zhipeng Shen, Yuanfang Wu, Xingze Huang, Zhongyuan Zhang, Jiangyu Liu, Qichun Wei, Wenhao Chen, Ye Chen, Liang Xu   +9 more
wiley   +1 more source

Glasgow prognostic score as a predictor of adjuvant nivolumab efficacy in esophageal squamous cell carcinoma. [PDF]

BMC Gastroenterol
Kara M, Ebinç S, Sezgin Y, Ürün M, Aldemir MN.   +4 more
europepmc   +1 more source

Long‐Term Prognosis and Immunotranscriptomic Landscape in Esophageal Squamous Cell Carcinoma With Different Pathological Responses to Neoadjuvant Chemoradiotherapy: A Retrospective Cohort Study

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This study comprehensively characterizes the long‐term prognosis and immunotranscriptomic landscape associated with different tumor regression grades (TRGs) in esophageal squamous cell carcinoma (ESCC) following neoadjuvant chemoradiotherapy. By integrating bulk RNA‐seq, single‐cell transcriptomics, and multiplexed immunohistochemistry, we demonstrate ...
Jianye Yuan, Zelin Weng, Xinke Zhang, Fangqi Deng, Zihui Tan, Jian Zhong, Rui Chen, Xiuying Xie, Xiaodan Lin, Ting Lin, Yan Huang, Qianwen Liu, Jing Wen, Jianhua Fu   +13 more
wiley   +1 more source

PRDM1: a useful indicator of differentiation and prognosis in esophageal squamous cell carcinoma. [PDF]

Diagn Pathol
Huang A, Jiang X, Qi Y, Chen J, Guo X, Lu J, Jin M.   +6 more
europepmc   +1 more source

Tumor Invasive Border Index (TIBI) in colorectal cancer: linking infiltrative morphology to molecular insights

The Journal of Pathology, Volume 270, Issue 1, Page 114-128, September 2026.
Abstract Tumor border configuration influences colorectal cancer (CRC) prognosis, yet its molecular determinants remain unclear and existing assessment criteria have faced challenges with reproducibility. We introduce the Tumor Invasive Border Index (TIBI), a novel and reproducible method that quantifies the proportion of tumor stroma and adipose ...
Akseli Kehusmaa, Jouni Härkönen, Huayi Li, Päivi Sirniö, Ville K Äijälä, Henna Karjalainen, Meeri Kastinen, Vilja V Tapiainen, Tuomo Mantere, Vesa‐Matti Pohjanen, Hanna Elomaa, Onni Sirkiä, Nicolas Pasquier, Maarit Ahtiainen, Olli Helminen, Erkki‐Ville Wirta, Taneli T Mattila, Outi Lindgren, Janette Savela, Jukka Rintala, Sanna Meriläinen, Juha Saarnio, Tero Rautio, Toni T Seppälä, Jan Böhm, Jukka‐Pekka Mecklin, Markus J Mäkinen, Anne Tuomisto, Johanna Ivaska, Juha P Väyrynen   +29 more
wiley   +1 more source

The survival impact of upfront or sequential chemoradiotherapy in locally advanced esophageal squamous cell carcinoma. [PDF]

Front Oncol
Luo X, Peng F, Lin X, Li Y, Ding Z.
europepmc   +1 more source

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang, Chung‐I Li, Rui Xin, Jijun Tang, Yan Guo   +4 more
wiley   +1 more source

ZNF750 suppresses esophageal squamous cell carcinoma by maintaining epithelial barrier-driven mucosal immune homeostasis. [PDF]

Biol Direct
Zhou T, Fan J, Wang M, Cheng C, Yuan F, Li J, Wan H, Cui D, Miao Y, Bi Y.   +9 more
europepmc   +1 more source