Results 61 to 70 of about 18,136 (239)

PD-1 inhibition in patient derived tissue cultures of human gastric and gastroesophageal adenocarcinoma

OncoImmunology, 2021
Emerging immunotherapies quest for better patient stratification in cancer treatment decisions. Moderate response rates of PD-1 inhibition in gastric and esophagogastric junction cancers urge for meaningful human model systems that allow for ...
Marlon Hußtegge, Ngoc Anh Hoang, Jakob Rebstock, Astrid Monecke, Ines Gockel, Arved Weimann, Guido Schumacher, Ingo Bechmann, Florian Lordick, Sonja Kallendrusch, Justus Körfer   +10 more
doaj   +1 more source

The Milan Score is an Effective Manometric Tool to Predict Gastroesophageal Reflux in Patients With Laryngopharyngeal Symptoms

Neurogastroenterology &Motility, EarlyView.
Patients with isolated LPS demonstrated a lower likelihood of EGJ disruption, pathologic GERD, and abnormal Milan score. The Milan score performed similarly well in the identification of GERD in both LPS and typical symptoms. The Milan score could therefore be used as an upfront test in LPS patients.
Stefano Siboni, Marco Sozzi, Pierfrancesco Visaggi, Ivan Kristo, Nicola De Bortoli, Salvatore Tolone, Elisa Marabotto, Daniele Bernardi, Sebastian F. Schoppmann, Roberto Penagini, Benjamin Rogers, Anthony Hobson, Jordan Haworth, Brian Louie, Yeong Yeh Lee, Vincent Tee, Takahiro Masuda, Dimitrios Theodorou, Tania Triantafyllou, Benedetta Barcella, Lorenzo Cusmai, Michele Puricelli, Marina Coletta, Vito Annese, Edoardo Vincenzo Savarino, Emanuele Luigi Giuseppe Asti, C. Prakash Gyawali   +26 more
wiley   +1 more source

HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

BMC Gastroenterology, 2020
Background Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC).
Anna Grenda, Kamila Wojas-Krawczyk, Tomasz Skoczylas, Paweł Krawczyk, Jadwiga Sierocińska-Sawa, Grzegorz Wallner, Janusz Milanowski   +6 more
doaj   +1 more source

Consensus on the Management of Anesthetic Agents During Digestive Motility Measurements and Proposal of a Standardized Protocol for Anesthesia (French Neuro Gastroenterology Group GFNG and Committee of Anesthetic French Experts)

Neurogastroenterology &Motility, EarlyView.
Anesthesia can alter measurements during digestive endoscopies, yet no standardized protocol currently exists. Two expert groups—the French Neuro‐Gastroenterology Group (GFNG) and anesthesiologists—used the Delphi method to reach a consensus on which drugs have an influence (91 amendments), ultimately resulting in a proposed anesthesia protocol (28 ...
Domitille Renard, Thomas Clavier, Osama Abou‐Arab, Gérard Amarenco, Emmanuel Besnier, Alice Blet, Matthieu Boisson, Charlène Brochard, Benoit Coffin, Audrey De Jong, Denis Frasca, Marc Garnier, Aurelie Gouel, Jérémie Jacques, Arthur James, Yoann Launey, Anne‐Marie Leroi, Chloé Melchior, Daphné Michelet, François Mion, Maxime Nguyen, Emmanuel Rineau, Amélie Rollé, Sabine Roman, Stéphanie Sigaut, Heithem Soliman, Fabien Wuestenberghs, Frank Zerbib, Guillaume Gourcerol, Charlotte Desprez   +29 more
wiley   +1 more source

Analysis of N6-Methyladenosine Methylome in Adenocarcinoma of Esophagogastric Junction

Frontiers in Genetics, 2022
Background: From previous studies, we found that there are more than 100 types of RNA modifications in RNA molecules. m6A methylation is the most common.
Jia-Bin Huang, Bin-Bin Hu, Rong He, Lian He, Chen Zou, Chang-Feng Man, Yu Fan   +6 more
doaj   +1 more source

Effect of pathologic tumor response and nodal status on survival in the medical research council adjuvant gastric infusional chemotherapy trial [PDF]

, 2016
Purpose: The Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) trial established perioperative epirubicin, cisplatin, and fluorouracil chemotherapy as a standard of care for patients with resectable esophagogastric cancer. However,
Allum, WH, Braconi, C, Cunningham, D, Fassan, M, Ghidini, M, Grabsch, HI, Hahne, JC, Lampis, A, Langley, R, Nankivell, M, Okines, AFC, Peckitt, C, Rugge, M, Smyth, EC, Valeri, N, Wotherspoon, A   +15 more
core   +7 more sources

Treatment Approaches to Esophagogastric Junction Tumors [PDF]

Digestive Surgery, 2013
Esophagogastric junction (EGJ) adenocarcinomas are usually classified into one of the three categories of the Siewert system. The clinicopathological features of EGJ adenocarcinomas vary according to this classification scheme. The lymphatic flow in EGJ tumors of any type is mainly toward the abdomen, and nodal metastasis to the upper or middle ...
Yukinori, Kurokawa, Mitsuru, Sasako, Yuichiro, Doki   +2 more
openaire   +2 more sources

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, Volume 158, Issue 9, Page 2219-2228, 1 May 2026.
What's new? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Macroscopic and histomorphometric analysis of the esophagogastric junction region of horses used for traction [PDF]

Biotemas, 2011
The esophagogastric junction was evaluated macroscopically and histologically, seeking to identify adaptive changes in a sample of six adult horses, being four males and two females, used for traction.
Eduardo Maurício Mendes de Lima, Marcelo Ismar Silva Santana, Márcio Botelho de Castro, Hildebrando Gomes Benedicto, Pedro Primo Bombonato, Laura Reis e Silva   +5 more
doaj  

Serosal patch of the gastroesophageal junction: an experimental study in dogs [PDF]

, 1998
Thirty two dogs were operated on in order to evaluate the mucosal regeneration of the serosal patch at the gastroesophageal junction. The operation began with a cardiotomy involving one centimeter of the esophagus and two centimeters of the stomach ...
Goldenberg, Saul, Magalhães, Albino, Mendelssonh, Paulo   +2 more
core   +3 more sources