Results 81 to 90 of about 21,359 (272)

Efficacy and safety of fruquintinib combined with albumin‐bound paclitaxel as second‐line therapy for advanced gastric cancer following failure of PD‐1 inhibitor‐containing treatment (TACTIC GC‐01): A phase II single‐arm study

International Journal of Cancer, Volume 158, Issue 9, Page 2219-2228, 1 May 2026.
What's new? Anti‐angiogenic drugs have shown promising efficacy as a second‐line treatment for advanced gastric cancer. However, it remains unclear how alterations in the tumor microenvironment following first‐line immunotherapy may impact tumor angiogenesis and influence subsequent therapeutic outcomes. This single‐arm study prospectively explored the
Xiaoting Ma, Kai Ou, Xiu Liu, Biyang Cao, Wenwei Yang, Jingyu Lu, Letian Zhang, Qi Wang, Lizhen Gao, Zhichao Jiang, Yongkun Sun, Lin Yang   +11 more
wiley   +1 more source

Three-Dimensional Myoarchitecture of the Lower Esophageal Sphincter and Esophageal Hiatus Using Optical Sectioning Microscopy. [PDF]

, 2017
Studies to date have failed to reveal the anatomical counterpart of the lower esophageal sphincter (LES). We assessed the LES and esophageal hiatus morphology using a block containing the human LES and crural diaphragm, serially sectioned at 50 μm ...
Cheng, Leo K, Kumar, Dushyant, Mittal, Ravinder K, Zifan, Ali   +3 more
core   +2 more sources

Prevalence of Esophageal Dysmotility and Reflux in Muscle Tension Dysphonia Patients

The Laryngoscope, Volume 136, Issue 5, Page 2206-2211, May 2026.
ABSTRACT Objectives Laryngopharyngeal reflux (LPR) contributes to muscle tension dysphonia (MTD); however, symptoms overlap with esophageal dysmotility. Study aims were to determine the prevalence of esophageal disorders among MTD patients and correlate pathologies to patient‐reported outcome measures (PROMs).
Megan Brianne Saltsgaver, Madison Cheung, Theo Covello, Weihai Zhan, Inna A. Husain   +4 more
wiley   +1 more source

Laparoscopic and left thoracoscopic Ivor-Lewis esophagectomy for Siewert type II esophagogastric junction cancer with right aortic arch: a case report

Surgical Case Reports, 2020
Background Right aortic arch (RAA) is a congenital malformation detected in 0.04% of the population without heterotaxia and makes esophagectomy and mediastinal lymphadenectomy difficult. A left thoracic approach is recommended in patients with RAA, but a
Motoki Murakami, Yasutaka Nakanishi, Yudai Hojo, Tatsuro Nakamura, Tsutomu Kumamoto, Yasunori Kurahashi, Yoshinori Ishida, Hisashi Shinohara   +7 more
doaj   +1 more source

Effect of pathologic tumor response and nodal status on survival in the medical research council adjuvant gastric infusional chemotherapy trial [PDF]

, 2016
Purpose: The Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) trial established perioperative epirubicin, cisplatin, and fluorouracil chemotherapy as a standard of care for patients with resectable esophagogastric cancer. However,
Allum, WH, Braconi, C, Cunningham, D, Fassan, M, Ghidini, M, Grabsch, HI, Hahne, JC, Lampis, A, Langley, R, Nankivell, M, Okines, AFC, Peckitt, C, Rugge, M, Smyth, EC, Valeri, N, Wotherspoon, A   +15 more
core   +7 more sources

Early‐Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites

Cancer Science, Volume 117, Issue 5, Page 1223-1234, May 2026.
Shared risk factors, clinical features, and tumor characteristics across multiple early‐onset cancer types are shown in this Graphical Abstract. Integrative approaches combining molecular pathology, oncology, and population sciences offer opportunities to clarify underlying mechanisms and help us develop preventive strategies for early‐onset cancers ...
Nobuhiro Nakazawa, Satoko Ugai, Atsushi Kondo, Kosuke Matsuda, Shu Kato, Genki Usui, Shiori Tanaka, Hwa‐Young Lee, Xinyuan Zhang, Hideo Miyagawa, Mai Chan Lau, Hiroshi Saeki, Yukihide Kanemitsu, Andrew T. Chan, Shuji Ogino, Minkyo Song, Juha P. Väyrynen, Tomotaka Ugai   +17 more
wiley   +1 more source

Operative surgery of the esophagogastric junction [PDF]

, 2013
A bibliographical review of the research presents the principal modern surgical operations which are performed for various pathology of the esophagogastric junction.
Tovkach, Y.V.
core  

Measurement of secondary esophageal motility by Endoluminal Functional Lumen Imaging Probe (EndoFLIP) in young patients with pediatric feeding disorder with and without persistent dysphagia

JPGN Reports, EarlyView.
Gurleen Kaur Kahlon, Sara Koroli, Phoenix Children's Statistician Group, Krisha Mansukhani, Lucia Mirea, Ricardo Medina‐Centeno, Dana I. Williams   +6 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

The evolution of views on the complex treatment of esophageal cancer

Вестник хирургии имени И.И. Грекова
INTRODUCTION. Currently, the choice of tactics in the treatment of esophageal cancer remains an urgent problem. Important factors are: the stage of the disease, the functional state of the patient, as well as the morphological type of tumor.
T. L. Sharapov, M. V. Burmistrov, E. I. Sigal, M. G. Gordiev, Ch. V. Kholomanova, V. I. Fedorov   +5 more
doaj   +1 more source