Results 71 to 80 of about 453,541 (160)

MET‐amplified gastric cancers exhibit co‐amplifications of BRAF, CDK6, and EGFR

The Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract MET‐positive gastric cancer (GC) has a poor prognosis. In addition, targeting MET with monoclonal antibodies or tyrosine kinase inhibitors had limited success. We searched for additional genetic alterations that might explain the poor outcome of MET‐positive GC and lack of response to MET‐targeted therapies.
Silke Lüschen, Ulrike Ebert, Hans‐Michael Behrens, Sandra Krüger, Dita Ulase, Anu Amallraja, Steffen M. Heckl, Thomas Becker, Philip Rosenstiel, Tobias Meißner, Christoph Röcken   +10 more
wiley   +1 more source

Role of Nampt and Visceral Adiposity in Esophagogastric Junction Adenocarcinoma

Journal of Immunology Research, 2017
Nampt including eNampt and iNampt may contribute to mediating obesity-associated cancers. This study investigated the role of Nampt in esophagogastric junction adenocarcinoma (EGA), a cancer strongly correlated with obesity.
Haijun Li, E. Bai, Yong Zhang, Zhuoqi Jia, Shicai He, Junke Fu   +5 more
doaj   +1 more source

Advances in Gastric Cancer Research: Insights Into Carcinogenesis, the Tumor Microenvironment, Metastasis, and Factors Influencing Prognosis

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 984-994, July 2026.
ABSTRACT Background The Department of Gastroenterological Surgery at Kumamoto University has maintained a commitment to integrating cutting‐edge clinical practice with fundamental research, particularly concerning malignant diseases of the digestive tract.
Hideo Baba, Takatsugu Ishimoto, Yoshifumi Baba, Hiromitsu Hayashi, Masaaki Iwatsuki   +4 more
wiley   +1 more source

Clinical Efficacy of Endoscopic Submucosal Dissection for Adenocarcinomas of the Esophagogastric Junction

Endoscopy International Open, 2014
Background and Study Aims There are a few reports about the efficacy of endoscopic submucosal dissection (ESD) for adenocarcinomas of the esophagogastric junction (EGJ).
Yasuaki Nagami, Hirohisa Machida, Masatsugu Shiba, Tomoko Obayashi, Masaki Ominami, Shusei Fukunaga, Satoshi Sugimori, Hirokazu Yamagami, Tetsuya Tanigawa, Kenji Watanabe, Toshio Watanabe, Kazunari Tominaga, Yasuhiro Fujiwara, Tetsuo Arakawa   +13 more
doaj   +1 more source

Risks and Benefits of Feeding Enterostomy Creation During Minimally Invasive Esophagectomy: A Propensity‐Weighted Analysis Using the Japanese National Clinical Database

Annals of Gastroenterological Surgery, Volume 10, Issue 4, Page 1042-1050, July 2026.
Feeding enterostomy during MIE was evaluated in 19 054 patients from the Japanese NCD using propensity weighting. Enterostomy was associated with higher reoperation and respiratory complications, but lower delayed gastric emptying and deep vein thrombosis, with no significant difference in overall bowel obstruction.
Eisuke Booka, Shinya Hirakawa, Hisateru Tachimori, Koji Tanaka, Hideki Ueno, Yasue Kimura, Ken Shirabe, Hiroya Takeuchi   +7 more
wiley   +1 more source

Years of Life Lost of Patients With Early Adenocarcinoma of the Esophagogastric Junction Compared to Esophageal or Gastric Adenocarcinoma. A Registry‐Based Study

Cancer Medicine, Volume 15, Issue 7, July 2026.
Notched Box‐and‐Whisker plots of years of life lost (YLL) comparing patients who died during the follow‐up with pT1 adenocarcinoma of the gastroesophageal junction. Patients with adenocarcinoma of the esophagus (EAC), cardia (CAC) or stomach (GAC) confined to the mucosa or submucosa lose a median of 10.7, 8.5 and 6.8 years of life, respectively ...
Elfriede Bollschweiler, Arnulf H. Hölscher, Brigitte Schumacher, Oliver Pech, Uta Drebber, in Cooperation with the German Cancer Registry, RKI   +6 more
wiley   +1 more source

Avelumab (anti–PD-L1) as first-line switch-maintenance or second-line therapy in patients with advanced gastric or gastroesophageal junction cancer: phase 1b results from the JAVELIN Solid Tumor trial

Journal for ImmunoTherapy of Cancer, 2019
Background We evaluated the antitumor activity and safety of avelumab, a human anti–PD-L1 IgG1 antibody, as first-line switch-maintenance (1 L-mn) or second-line (2 L) treatment in patients with advanced gastric/gastroesophageal cancer (GC/GEJC ...
Hyun Cheol Chung, Hendrik-Tobias Arkenau, Jeeyun Lee, Sun Young Rha, Do-Youn Oh, Lucjan Wyrwicz, Yoon-Koo Kang, Keun-Wook Lee, Jeffrey R. Infante, Sung Sook Lee, Margaret Kemeny, Ulrich Keilholz, Bohuslav Melichar, Alain Mita, Ruth Plummer, Denis Smith, Arnold B. Gelb, Huiling Xiong, Janet Hong, Vikram Chand, Howard Safran   +20 more
doaj   +1 more source

Descriptors of Participants Eligible for Analysis of Heartburn/Regurgitation in Relation to Esophageal Adenocarcinoma and Esophagogastric Junction Adenocarcinoma.

, 2014
The median and interquartile range of each variable are provided, unless the variable is stated to be a percentage in which case the percentage and 95 percent confidence interval are provided.
Anna H. Wu (193241), David C. Whiteman (35608), Farin Kamangar (63964), Michael B. Cook (430834), Douglas A. Corley (606201), Harvey A. Risch (458625), Thomas L. Vaughan (229013), Leslie Bernstein (3467), Olof Nyrén (199747), Marilie D. Gammon (18349), Wong-Ho Chow (197825), Neal D. Freedman (340880), Nirmala Pandeya (606203), Weimin Ye (20887), Liam J. Murray (606202), Linda M. Liao (197806), Alan G. Casson (591232)   +16 more
core   +1 more source

CT-based radiomics nomogram to predict response of advanced adenocarcinoma of esophagogastric junction to neoadjuvant chemotherapy

Insights into Imaging
Objective To establish and validate a CT-based radiomics model to predict the response of adenocarcinoma of the esophagogastric junction (AEG) to neoadjuvant chemotherapy (NAC).
Chuan-qinyuan Zhou, Yue-su Wang, Wen-han Liao, Jing-ke Li, Xin-yi Liao, Yan Gui, Xiao-ming Zhang, Tian-wu Chen   +7 more
doaj   +1 more source

Prevalence of adenocarcinoma of the esophagogastric junction through a Moroccan study [PDF]

, 2012
L’adénocarcinome de la jonction œsogastrique est une entité récente. Sa fréquence augmente dans le monde surtout occidental. Le but de cette étude marocaine est d’évaluer la prévalence de l’adénocarcinome de la jonction œso-gastrique et d’étudier les ...
Salihoun, Mouna, Kabbaj, Nawal, Nya, Mohamed, Chaoui, Zakia, Acharki, Mohamed, Amrani, Laïla, Saké, Khadidjatou, Amrani, Naima, Serraj, Ilham   +8 more
core   +1 more source