Results 131 to 140 of about 347,041 (314)

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Ecoendoscopia: Parte I Endoscopic ultrasonography

Revista Colombiana de Cirugía, 2008
La ecoendoscopia es un examen que combina la imagen de endoscopia con la ecográfica para valorar no sólo las lesiones del interior de la luz sino las lesiones que rodean al tubo digestivo.
Martín Gómez
doaj  

Extensive Squamous Papillomatosis of the Esophagus

, 2013
J Pohl
openalex   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

Advanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang, Ruiying Qiang, Yuan Zhang, Jinxian Wan, Chen Tao, Ying Dong, Xujun Tang, Li Xu, Hairong Xiao, Yanqin Lin, Wei Tong, Ying Ma, Yongming Wang, Peng Li, Renjie Chai   +14 more
wiley   +1 more source

A CASE OF ADENOID CYSTIC CARCINOMA OF THE ESOPHAGUS

, 1998
Shinichi Murakami, Tsuyoshi Hashimoto, Shinsuke Takeno, Shinsuke HAZAMADA, Yuzo Uchida, Shigeo Yokoyama   +5 more
openalex   +2 more sources

Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients With Barrett’s Esophagus

, 2021
Christopher Douville, Helen Moinova, Prashanthi N. Thota, Nicholas J. Shaheen, Prasad G. Iyer, Marcia Irene Canto, Jean S. Wang, John A. Dumot, Ashley L. Faulx, Kenneth W. Kinzler, Nickolas Papadopoulos, Bert Vogelstein, Sanford D. Markowitz, Chetan Bettegowda, Joseph Willis, Amitabh Chak   +15 more
openalex   +2 more sources

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Total esophagogastrectomy in the neoplasms of the esophagus and esofagogastric junction: when must be indicated? [PDF]

, 2015
Nelson Adami Andreollo, João de Souza Coelho Neto, G. D. Calomeni, Luiz Roberto Lopes, Valdir Tercioti   +4 more
openalex   +1 more source

Biomechanics‐Driven 3D Architecture Inference from Histology Using CellSqueeze3D

Advanced Science, EarlyView.
CellSqueeze3D reconstructs 3D cellular architecture from standard 2D histology images using biomechanical constraints and optimization. Validated on clinical datasets, it enables accurate tissue phenotyping, predicts gene mutations, and reveals significant correlations between nuclear‐cytoplasmic ratio entropy and tumor progression.
Yan Kong, Hui Lu
wiley   +1 more source

Lysyl Oxidase Mediates Proliferation and Differentiation in the Esophageal Epithelium

Biomolecules
In homeostatic conditions, the basal progenitor cells of the esophagus differentiate into a stratified squamous epithelium. However, in the setting of acid exposure or inflammation, there is a marked failure of basal cell differentiation, leading to ...
Kanak V. Kennedy, Joshua X. Wang, Emily McMillan, Yusen Zhou, Ryugo Teranishi, Ann Semeao, Leena Mirchandani, Chizoba N. Umeweni, Diya Dhakal, Alyssa Baccarella, Satoshi Ishikawa, Masaru Sasaki, Takefumi Itami, Adele C. Harman, Leonel Joannas, Tatiana A. Karakasheva, Hiroshi Nakagawa, Amanda B. Muir   +17 more
doaj   +1 more source