Results 131 to 140 of about 378,407 (392)

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

open access: yesAdvanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song   +9 more
wiley   +1 more source

Jackhammer esophagus: high-resolution manometry and therapeutic approach using peroral endoscopic myotomy (POEM).

open access: yesDiseases of the esophagus, 2016
We present the first report on peroral endoscopic myotomy (POEM) in the treatment of jackhammer esophagus. A 34-year-old female patient was newly diagnosed with a jackhammer esophagus.
A. Kandulski   +3 more
semanticscholar   +1 more source

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

open access: yesAdvanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao   +14 more
wiley   +1 more source

Thoracoscopy in pediatrics: Surgical perspectives

open access: yesAnnals of Thoracic Medicine, 2019
Thoracoscopic surgery and other minimally invasive approaches in children achieved marked advancement and expanded to include several disciplines in the last decade.
Osama A Bawazir
doaj   +1 more source

CONGENITAL ATRESIA OF THE ESOPHAGUS [PDF]

open access: green, 1918
Joseph Brennemann
openalex   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang   +13 more
wiley   +1 more source

Odinofagia em paciente com pênfigo vulgar de esôfago sem alterações dermatológicas: relato de caso

open access: yesRevista Dor
JUSTIFICATIVA E OBJETIVOS: Pênfigo refere-se a um grupo de doenças bolhosas intraepidérmicas imuno-mediadas, caracterizadas pela perda de coesão entre as células epidérmicas. As lesões bolhosas podem envolver pele e mucosas.
Ana Carolina Bastos Magalhães   +5 more
doaj   +1 more source

The Foundational Model of Anatomy Ontology [PDF]

open access: yes, 2007
Anatomy is the structure of biological organisms. The term also denotes the scientific discipline devoted to the study of anatomical entities and the structural and developmental relations that obtain among these entities during the lifespan of an ...
Mejino, Jose L V, Rosse, Cornelius
core   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

open access: yesAdvanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang   +10 more
wiley   +1 more source

The Prevalence of Human Papilloma Virus in Esophageal Squamous Cell Carcinoma [PDF]

open access: yesIranian Journal of Medical Sciences, 2012
Background: Carcinomas of esophagus, mostly squamous cell carcinomas, occur throughout the world. There are a number of suspected genetic or environmental etiologies. Human papilloma virus (HPV) is said to be a major etiology in areas with high incidence
Sadat Noori   +2 more
doaj  

Home - About - Disclaimer - Privacy