Results 21 to 30 of about 241,618 (304)

Nipped-B-like Protein Sensitizes Esophageal Squamous Cell Carcinoma Cells to Cisplatin via Upregulation of PUMA

Technology in Cancer Research & Treatment, 2020
Nipped-B-like protein plays a pivotal role as a cohesin loading factor in the segregation of chromosomes when cells divide. Accumulating evidence indicates that alterations of this protein are involved in human carcinogenesis, especially in the ...
Shengjie Zhang PhD, Yun Zhou BM, Qinchuan Wang MD, PhD, Kristine Donahue PhD, Jianguo Feng MMed, Yinli Yao MMed, Aiping Chen PhD, Xia Li PhD, Lianlian Hong PhD   +8 more
doaj   +1 more source

Critical Competences for the Management of Post-Operative Course in Patients with Digestive Tract Cancer: The Contribution of MADIT Methodology for a Nine-Month Longitudinal Study

Behavioral Sciences, 2022
There is a high postoperative morbidity rate after cancer surgery, that impairs patients’ self-management, job condition and economic strength. This paper describes the results of a peculiar psychological intervention on patients undergoing surgery for ...
Eleonora Pinto, Alessandro Fabbian, Rita Alfieri, Anna Da Roit, Salvatore Marano, Genny Mattara, Pierluigi Pilati, Carlo Castoro, Marco Cavarzan, Marta Silvia Dalla Riva, Luisa Orrù, Gian Piero Turchi   +11 more
doaj   +1 more source

Complete pathological response of colorectal peritoneal metastases in Lynch syndrome after immunotherapy case report: is a paradigm shift in cytoreductive surgery needed?

BMC Gastroenterology, 2022
Background We report the first case of a patient affected by peritoneal metastases from colon cancer, arising in the context of Lynch syndrome with pathological complete response. The patient was treated with immunotherapy and cytoreductive surgery. This
Marco Tonello, Floriana Nappo, Loretta Vassallo, Rosa Di Gaetano, Carla Davoli, Elisa Pizzolato, Ottavia De Simoni, Cristina Tassinari, Antonio Scapinello, Pierluigi Pilati, Fotios Loupakis, Sara Lonardi, Antonio Sommariva   +12 more
doaj   +1 more source

Milestones in the History of Esophagectomy: From Torek to Minimally Invasive Approaches

Medicina, 2023
The history of esophagectomy reflects a journey of dedication, collaboration, and technical innovation, with ongoing endeavors aimed at optimizing outcomes and reducing complications.
Pascal Alexandre Thomas
doaj   +1 more source

Current Status of Endoscopic Vacuum Therapy in the Management of Esophageal Perforations and Post-Operative Leaks [PDF]

Clinical Endoscopy, 2021
Esophageal wall defects, including perforations and postoperative leaks, are associated with high morbidity and mortality and pose a significant management challenge.
Imogen Livingstone, Lily Pollock, Bruno Sgromo, Sotiris Mastoridis   +3 more
doaj   +1 more source

Clinical significance of VEGF-A, -C and -D expression in esophageal malignancies [PDF]

, 2005
Vascular endothelial growth factors ( VEGF)- A, - C and - D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D
Jauch, Karl-Walter, Kleespies, A., Bruns, Christiane J.   +2 more
core   +1 more source

Microbiota Detection Patterns Correlate With Presence and Severity of Barrett’s Esophagus

Frontiers in Cellular and Infection Microbiology, 2021
BackgroundThe microbiome has been increasingly associated with different disease processes, but its role in esophagus is largely unknown. Our goal was to determine the associations of the esophageal microbiota with Barrett’s esophagus.MethodsA total of ...
Ikenna C. Okereke, Aaron L. Miller, Daniel C. Jupiter, Catherine F. Hamilton, Gabriel L. Reep, Timothy Krill, Clark R. Andersen, Richard B. Pyles   +7 more
doaj   +1 more source

MGMT promoter methylation and 1p/19q co-deletion of surgically resected pulmonary carcinoid and large-cell neuroendocrine carcinoma

World Journal of Surgical Oncology, 2018
Background The response to temozolomide (TMZ) treatment in small-cell lung cancer (SCLC) correlated with O(6)-methylguanine -DNA methyltransferase (MGMT) promoter methylation. 1p/19q co-deletion within oligodendroglioma is a responsive predictor for TMZ.
Lei Lei, Zhiming Jiang, Gu Zhang, Qiaoyuan Cheng, Hongyang Lu   +4 more
doaj   +1 more source

Managing the Consequences of Oncological Major Surgery: A Short- and Medium-Term Skills Assessment Proposal for Patient and Caregiver through M.A.D.I.T. Methodology

Behavioral Sciences, 2022
The effects of cancer surgery and treatment harm patients’ life and working ability: major causes of this can be intensified by the postoperative symptoms.
Gian Piero Turchi, Alessandro Fabbian, Rita Alfieri, Anna Da Roit, Salvatore Marano, Genny Mattara, Pierluigi Pilati, Carlo Castoro, Davide Bassi, Marta Silvia Dalla Riva, Luisa Orrù, Eleonora Pinto   +11 more
doaj   +1 more source

Impact of Age on Short- and Long-Term Outcomes after Pancreatoduodenectomy for Periampullary Neoplasms

Gastroenterology Research and Practice, 2020
Background. Although mortality and morbidity of pancreatoduodenectomy (PD) have improved significantly over the past years, the impact of age for patients undergoing PD is still debated.
Mario Gruppo, Francesca Tolin, Boris Franzato, Pierluigi Pilati, Ylenia Camilla Spolverato, Francesca Zingales, Imerio Angriman, Romeo Bardini   +7 more
doaj   +1 more source