Results 31 to 40 of about 198,266 (267)

Identification of potential drug targets and possible drugs for esophageal carcinoma from genetic insights: a comprehensive two-sample Mendelian randomization study

open access: yesDiscover Oncology
Background Esophageal carcinoma (EC) is the eighth most common cancer, which is a major health problem on a global scale. Comprehensive treatments such as surgery, radiotherapy and chemotherapy have demonstrated efficacy in certain patients with early ...
Juan Wang   +7 more
doaj   +1 more source

Approach of Dysphagia

open access: yesThe Korean Journal of Gastroenterology, 2021
Dysphagia has been reported to be relatively common and seems to be increased in Korea. Dysphagia can be classified as oropharyngeal dysphagia or esophageal dysphagia.
Moo In Park
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Two Distinct Types of Hypercontractile Esophagus: Classic and Spastic Jackhammer

open access: yesGut and Liver, 2016
Hypercontractile esophagus (nicknamed jackhammer esophagus) is a recently defined disease within the esophageal motility disorders classification. Responses to treatments for jackhammer esophagus have been inconsistent in previous trials, possibly due to
Yun Soo Hong   +2 more
doaj   +1 more source

Robot‐assisted minimally invasive esophagectomy for esophageal cancer: Meticulous surgery minimizing postoperative complications

open access: yesAnnals of Gastroenterological Surgery, 2020
Minimally invasive esophagectomy (MIE) has been reported to reduce postoperative complications especially pulmonary complications and have equivalent long‐term survival outcomes as compared to open esophagectomy.
Kei Hosoda   +4 more
doaj   +1 more source

Optional Management of Achalasia in 2021: Dilatation or Myotomy

open access: yesJournal of Digestive Endoscopy, 2021
Achalasia cardia is a primary motility disorder of the esophagus, defined by lack of normal esophageal peristalsis along with inadequate relaxation of lower esophageal sphincter .
Zaheer Nabi   +2 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

A hook in the esophagus [PDF]

open access: yesQJM, 2013
This is a 34-month-old female without history of systemic illness. She had been admitted before for bronchopneumonia and endoscopic removal of accidentally swallowed coins. This time, she was admitted due to odynophagia and sorethroat for 1 day. There was no other systemic …
openaire   +2 more sources

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer   +11 more
wiley   +1 more source

Carcinoid of the Esophagus Concomitant with Adenocarcinoma of the Esophagus: One Case Report and Literature Review

open access: yesCancer Biology & Medicine, 2010
Neuroendocrine tumors of the esophagus are derived from thediffuse neuroendocrine system in the gastrointestinal tract. Neuroendocrine tumors in the esophagus can be distinguished from othermesenchymal tumors by immunostaining for synaptophysin and ...
Bei-bei XU, Li-hui PAN, Chun-hui LI
doaj   +1 more source

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