Results 61 to 70 of about 340,355 (361)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Treating esophageal cancer with synchronous or antecedent head and neck cancers: a more formidable challenge?

, 2004
link_to_subscribed_fulltextThe 9th World Congress of the International Society for Diseases of the Esophagus, Madrid, Spain, 27-29 May 2004. In Diseases of the Esophagus, 2004, v. 17 suppl. 1, p.
Wong, J, Lo, OSH, Wei, WI, Kwok, KF, Wong, KH, Law, SYK, Lam, LK   +6 more
core   +3 more sources

Identification of potential drug targets and possible drugs for esophageal carcinoma from genetic insights: a comprehensive two-sample Mendelian randomization study

Discover Oncology
Background Esophageal carcinoma (EC) is the eighth most common cancer, which is a major health problem on a global scale. Comprehensive treatments such as surgery, radiotherapy and chemotherapy have demonstrated efficacy in certain patients with early ...
Juan Wang, Ji Sun, Chen Liang, Haibin Ou, Jiong Liu, Aoqing Ye, Qiuji Wu, Yu Liu   +7 more
doaj   +1 more source

Approach of Dysphagia

The Korean Journal of Gastroenterology, 2021
Dysphagia has been reported to be relatively common and seems to be increased in Korea. Dysphagia can be classified as oropharyngeal dysphagia or esophageal dysphagia.
Moo In Park
doaj   +1 more source

Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus

, 2013
AIM: To assess tumour regression grade (TRG) and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS: Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal ...
Kelly, Jamie, Iveson, T., Underwood, T.J., Rees, Charlotte, Bailey, Ian, Bateman, Andrew R., Byrne, James, Sharland, Donna, Noble, Fergus, Bateman, Adrian C., Nolan, Luke   +10 more
core   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Two Distinct Types of Hypercontractile Esophagus: Classic and Spastic Jackhammer

Gut and Liver, 2016
Hypercontractile esophagus (nicknamed jackhammer esophagus) is a recently defined disease within the esophageal motility disorders classification. Responses to treatments for jackhammer esophagus have been inconsistent in previous trials, possibly due to
Yun Soo Hong, Yang Won Min, Poong-Lyul Rhee   +2 more
doaj   +1 more source

Robot‐assisted minimally invasive esophagectomy for esophageal cancer: Meticulous surgery minimizing postoperative complications

Annals of Gastroenterological Surgery, 2020
Minimally invasive esophagectomy (MIE) has been reported to reduce postoperative complications especially pulmonary complications and have equivalent long‐term survival outcomes as compared to open esophagectomy.
Kei Hosoda, Masahiro Niihara, Hiroki Harada, Keishi Yamashita, Naoki Hiki   +4 more
doaj   +1 more source

Optional Management of Achalasia in 2021: Dilatation or Myotomy

Journal of Digestive Endoscopy, 2021
Achalasia cardia is a primary motility disorder of the esophagus, defined by lack of normal esophageal peristalsis along with inadequate relaxation of lower esophageal sphincter .
Zaheer Nabi, Mohan Ramchandani, D. Nageshwar Reddy   +2 more
doaj   +1 more source

Time Trends of Endoscopic and Pathological Diagnoses Related to Gastroesophageal Reflux Disease in a Chinese Population: Eight Years Single Institution Experience

, 2011
P>The discrepancy between Eastern and Western countries exists regarding the time trends of Barrett's esophagus (BE) /adenocarcinoma. We aimed to elucidate this issue through a retrospective review of the endoscopic and pathological diagnoses of ...
CHEN, MEI-JYH;LEE, YI-CHIA;CHIU, HAN-MO;WU, MING-SHIANG;WANG, HSIU-PO;LIN, JAW-TOWN, 陳美志;李宜家;邱瀚模;吳明賢;王秀伯;林肇堂   +1 more
core   +1 more source