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Combined Effect of per- and Polyfluoroalkyl Substances, Toxic Metals, and Essential Elements on Chronic Kidney Disease [PDF]
PollutantsChronic kidney disease (CKD) is a noteworthy global health issue affecting 10% of the world’s populace. It is increasingly linked to environmental exposures; however, the interplay of toxic metals, per- and polyfluoroalkyl substances (PFAS), and ...
Issah Haruna, Emmanuel Obeng-Gyasi
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Essential elements for nuclear binding
Physics Letters B, 2019 How does nuclear binding emerge from first principles? Our current best understanding of nuclear forces is based on a systematic low-energy expansion called chiral effective field theory.
Bing-Nan Lu +5 more
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Ageing-associated effects of a long-term dietary modulation of four trace elements in mice
Redox Biology, 2021 Trace elements (TEs) are essential for diverse processes maintaining body function and health status. The complex regulation of the TE homeostasis depends among others on age, sex, and nutritional status.
Viktoria K. Wandt +16 more
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Are trace element concentrations suitable biomarkers for the diagnosis of cancer?
Redox Biology, 2021 Despite advances in cancer research, cancer is still one of the leading causes of death worldwide. An early diagnosis substantially increases the survival rate and treatment success.
Kristina Lossow +2 more
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Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P
Nature Communications, 2023 Selenium homeostasis depends on hepatic biosynthesis of selenoprotein P (SELENOP) and SELENOP-mediated transport from the liver to e.g. the brain. In addition, the liver maintains copper homeostasis. Selenium and copper metabolism are inversely regulated,
Maria Schwarz +24 more
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A matter of concern – Trace element dyshomeostasis and genomic stability in neurons
Redox Biology, 2021 Neurons are post-mitotic cells in the brain and their integrity is of central importance to avoid neurodegeneration. Yet, the inability of self-replenishment of post-mitotic cells results in the need to withstand challenges from numerous stressors during
Viktoria K. Wandt +8 more
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Frontiers in Endocrinology, 2023 Mitochondria play multifaceted roles in cellular function, and impairments across domains of mitochondrial biology are known to promote cellular integrated stress response (ISR) pathways as well as systemic metabolic adaptations.
Carla Igual Gil +16 more
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Redox Biology, 2023 Five out of eight human glutathione peroxidases (GPXs) are selenoproteins, representing proteins that contain selenium as part of the amino acid selenocysteine. The GPXs are important for reducing hydroperoxides in a glutathione-consuming manner and thus
Maria Schwarz +7 more
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Essential and toxic elements concentrations in animal tissues of sheep from two different regions of Slovakia [PDF]
Acta Fytotechnica et Zootechnica, 2020 Animal products and meat from farm animals are consumed daily and it is very good source of animal proteins, but consumer´s information about exposure to heavy metals in meat and it´s health risk is in general low.
Martina Pšenková, Róbert Toman
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Copper interferes with selenoprotein synthesis and activity
Redox Biology, 2020 Selenium and copper are essential trace elements for humans, needed for the biosynthesis of enzymes contributing to redox homeostasis and redox-dependent signaling pathways.
Maria Schwarz +8 more
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