Results 51 to 60 of about 1,333,469 (384)
Background Dry eye is a common, complex condition that can reduce ocular comfort and visual performance. The impact on quality of life has been rated as similar to the effect of moderate angina and, in more severe cases, dialysis and severe angina.
Ai-hua Liu, J. Ji
semanticscholar +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Biochemical composition of different body parts of Gafrarium tumidum (Roding, 1798) from Mandapam, South East Coast of India [PDF]
Due to its abundance in various areas along the Mandapam coast (latitude 9° 17”N; longitude 79° 11”E), Southeast coast of India, the commonly occurring intertidal bivalve Gafrarium tumidum was selected for this study to investigate its nutritive value.
Babu, A, Rajagopal, S, Venkatesan, V
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Nutritional and phenolic profile of small edible fungal species Coprinellus disseminatus (pers.) J.E. Lange 1938 [PDF]
The aim of this work was to investigate nutritional profile in relation to proteins, amino acids, fatty acids and mineral composition, as well as phenolic profile of small edible fungal species Coprinellus disseminatus originated from Serbia.
Novaković Aleksandra R. +6 more
doaj +1 more source
The effect of frozen storage on lipids and fatty acids content in Atlantic salmon. Case study [PDF]
Being a species appreciated in all parts of the world, the demand for salmon will always be high. Keeping frozen in the entire period of distribution and handling is a way to increase "shelf life". During cold storage, fish fat can be altered.
Badulescu, Liliana +5 more
core
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Is fat the sixth taste primary? Evidence and implications [PDF]
Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Andrew Costanzo, Russell Keast
core +1 more source
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Background: Long-chain polyunsaturated fatty acids (LC-PUFA) are nutritionally important constituents of breast milk to support normal growth, immune function and central nervous system development of newborn infants.
Boué-Vaysse Carole +6 more
doaj +1 more source

