Results 141 to 150 of about 908,196 (265)

Quantitative ex vivo assessment of target temperature and ablation duration for protocol optimization of microwave ablation procedures with mr thermometry. [PDF]

Sci Rep
Nardone L, Tan ASM, Bour P, Fabritius MP, Öcal E, Schmidt VF, Wu M, Bauer LM, Ozenne V, Ricke J, Seidensticker M, Dietrich O.   +11 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

From Voxel-wise Fitting to Generative Translation: A Path for Quantitative DCE MRI Analysis in Breast Cancer. [PDF]

Radiol Imaging Cancer
Zhang J.
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Explainable deep learning for skin cancer detection using swish-activated convolutional networks. [PDF]

Discov Oncol
Mukherjee S, Chandrakar K, Chowdhury S, Senniappan V, Roy B, Panigrahi A, Pati A, Sahu B, Kant S.   +8 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Integrated 3D static modelling to assess hydrocarbon potential of the fluvial-alluvial sandstones of Nukhul Formation, October oil field, Gulf of Suez, Egypt. [PDF]

Sci Rep
Khattab MA, Radwan AE, El-Anbaawy MI, El-Tehiwy AA.   +3 more
europepmc   +1 more source

Disjoint essential circuits in toroidal maps [PDF]

, 1993
Bojan Mohar, Neil Robertson
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Gastric intestinal metaplasia: Management and surveillance strategies. [PDF]

World J Gastrointest Pathophysiol
Attieh P, Al Hazzouri A, Al Qassab M, Mansour E, Rizk N, Karam K, Fiani E, Farhat SG.   +7 more
europepmc   +1 more source