Results 271 to 280 of about 6,492,121 (341)

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral Deep Brain Stimulation and Probabilistic Lesion Mapping. [PDF]

Mov Disord
Sarica C, Yamamoto K, Iorio-Morin C, Germann J, Yang AZ, Santyr B, Colditz M, Vetkas A, Fomenko A, Davidson B, Schmidt F, Grippe T, Samuel N, Zemmar A, Flouty O, Cheyuo C, Darmani G, Chen R, Boutet A, Neudorfer C, Hodaie M, Kalia SK, Munhoz RP, Fasano A, Lozano AM.   +24 more
europepmc   +1 more source

Quantitative essentiality in a reduced genome: a functional, regulatory and structural fitness map

Samuel Miravet‐Verde, Raul Burgos, Eva Garcia‐Ramallo, Marc Weber, Luís Serrano   +4 more
openalex   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Fine-Scale Risk Mapping for Dengue Vector Using Spatial Downscaling in Intra-Urban Areas of Guangzhou, China. [PDF]

Insects
Shen Y, Ren Z, Fan J, Xiao J, Zhang Y, Liu X.   +5 more
europepmc   +1 more source

Essential Dynamics for Lorenz maps on the real line and the Lexicographical World

, 2006
Carlos Gustavo Moreira, Rafael Labarca
openalex   +2 more sources

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

Molecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza, Robert Carlsson, Coralie Gamper, Gayatri Chitale, Johan Bengzon, Gesine Paul   +5 more
wiley   +1 more source

Multi robot exploration using an advanced multi-objective salp swarm algorithm for efficient coverage and performance. [PDF]

Sci Rep
El Romeh A, Mirjalili S.
europepmc   +1 more source

A financial road map to scaling up essential child health interventions in 75 countries

, 2007
Karin Stenberg
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source