Results 261 to 270 of about 1,622,202 (352)

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

Advanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone, Giorgia Imparato, Chiara Ausilio, Valentina Mollo, Paolo Antonio Netti   +4 more
wiley   +1 more source

Nano-encapsulated <i>Senecio glaucus</i> L. essential oil with potent antioxidant, anticancer, and wound-healing properties. [PDF]

RSC Adv
Hussein ZH, Hammad SF, Shimizu K, Nassrallah AA, Soliman HSM.   +4 more
europepmc   +1 more source

Chemical characterization and biological activity assessment of Atriplex halimus essential oil: exploring new avenues in pharmacology and medicine

Kerzabi Rachida, Aouadj Sid Ahmed, Chikhi Ilyas, Boussaid Khadidja, Lafri Imène, Muselli Alain   +5 more
openalex   +2 more sources

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Development of perilla essential oil-based nanoemulsions as anti-psoriatic and dermal delivery platforms for topical therapy. [PDF]

Int J Pharm X
Zhang Z, Mu J, Tao S, Li T, Lunter DJ, Bao Z, Chen Y, Cai L, Cao P, Liu Y.   +9 more
europepmc   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Impact of Dry and Rainy Seasons on the Chemical Profile and Antioxidant Activity of <i>Lippia alba</i> Essential Oil. [PDF]

Molecules
Dias Alves R, Bauman Quieregati JP, Pereira de Souza JS, Brandão-Silva MH, Pereira da Silva A, Scortecci KC, do Carmo Barreto J, Oliveira Rocha HA.   +7 more
europepmc   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Experimental and molecular docking analyses of antibacterial activity in moroccan Rosmarinus officinalis essential oil. [PDF]

Sci Rep
Lahlou Y, Elorchi S, Dakir M, Salah M, Ezzouine N, Belfaiza M, Makroum K, Maissour A.   +7 more
europepmc   +1 more source

In vitro sensitivity of Brachyspira hyodysenteriae to organic acids and essential oil components [PDF]

, 2013
Boyen, Filip, De Pauw, Nele, Haesebrouck, Freddy, Heyndrickx, Marc, Maes, Dominiek, Mahu, Maxime, Martel, An, Pasmans, Frank, Vande Maele, Lien, Verlinden, Marc   +9 more
core   +1 more source