Results 61 to 70 of about 6,038,217 (384)

Characterization and Antimicrobial Activity of Biodegradable Active Packaging Enriched with Clove and Thyme Essential Oil for Food Packaging Application

open access: yesFoods, 2020
Bioactive packaging contains natural antimicrobial agents, which inhibit the growth of microorganisms and increase the food shelf life. Solvent casting method was used to prepare the Poly (lactide)-Poly (butylene adipate-co-terephthalate) (PLA-PBAT) film
Shubham Sharma   +4 more
semanticscholar   +1 more source

Phenotypic Variations and Bioactive Constituents among Selected Ocimum Species

open access: yesPlants, 2023
Basil (Ocimum species) represents an extraordinary group of aromatic plants that have gained considerable economic importance, primarily due to their essential oils, which have applications in medicine, culinary, and perfumery.
Sintayehu Musie Mulugeta   +2 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Nutritional and bioactive compound analysis of mangosteen fruit in hill and flat land plantations, during both the season and off-season, in provinces along the Gulf of Thailand and the Andaman Sea

open access: yesNFS Journal
This study examined the nutritional, physicochemical, and bioactive compounds in mangosteen grown in southern Thailand from 2022 to 2024, encompassing hilly areas (Nakhon Si Thammarat range, Tenasserim range) and flat lands during both the fruit season ...
Narumol Matan   +3 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Synthetic Endocrine Disruptors in Fragranced Products

open access: yesEndocrines
Endocrine disruptors are molecules that can interfere with the proper functioning of the endocrine system and lead to harmful effects in living organisms.
Sawyer Ashcroft   +3 more
doaj   +1 more source

Rancang Bangun Sistem Peningkatan Kinerja Rantai Pasok Industri Minyak Atsiri [PDF]

open access: yes, 2014
. Competitiveness of Indonesian essential oil industry is still low as efficiency is low. One of production system that has an aim to do efficiency, that are lowering cost, reducing lead time (faster delivery), higher quality is lean production system ...
Efendi, E. (Efendi)   +3 more
core   +1 more source

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