Results 71 to 80 of about 3,269,110 (305)

Comparative Study of Antibacterial Activity between Selected International and Indian Essential Oils against Selected Pathogenic Bacteria [PDF]

open access: yes
In recent years, the rapid growth in Antimicrobial resistance (AMR) has become a global concern. Essential oils derived from plants that include bioactive components with proven antioxidative and antibacterial activities could be a potential solution to ...
K.V. Leela   +3 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

From honey to functional powder: Drying technologies, carrier agents, and industrial applications [PDF]

open access: yesBIO Web of Conferences
A stable powdered form of natural honey can be obtained through drying processes, which helps overcome several technological limitations associated with liquid honey.
Aliji Sokol
doaj   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Antibacterial Properties of Ajuga chamaecistus Subsp. Scoparia and Chemical Composition of its Oils [PDF]

open access: yesJournal of Medicinal Plants and By-products, 2016
In the present study, we reported the essential oils chemical composition and antibacterial activities of the aerial parts of Ajuga chamaecistus Ging. ex Benth. Subsp. Scoparia (Boiss.) Rech.f.
Abdolrasoul Haghir Ebrahimabadi   +3 more
doaj  

Effect of sucrose replacement on physicochemical parameters and sensory characteristics of instant coffee drinks [PDF]

open access: yesBIO Web of Conferences
Coffee is one of the most popular drinks in the world. There has been a trend in consumer behaviour over the last few years - a change in the traditional way of consuming coffee.
Hadjikinova Raina, Petrova Ivanka
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

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