Results 81 to 90 of about 3,119,098 (305)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Comparative study on sensory and rheology characteristics of chocolate products obtained from cocoa beans roasted in different conditions [PDF]

BIO Web of Conferences
Roasting conditions of cocoa beans, used in chocolate production, were evaluated in the following study as one of the main factors determine quality of the chocolate products.
Petrova Ivanka, Djurkov Georgi, Hadjikinova Raina   +2 more
doaj   +1 more source

Essential oils: History, biosynthesis, and agronomic aspects

, 2012
Essential oils constitute important raw materials for the food, beverage,pharmaceutical, and perfumery industries. The production and chemical composition ofessential oils are influenced by genetic and agronomic factors, among others.
Facanali, Roselaine, Vieira, Maria Ap. R. [UNESP], Haber, Lenita L., Marques, Marcia Ortiz M.   +3 more
core  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Volatile constituents and larvicidal activity of the essential oils from three Nigerian medicinal plants

, 2015
Larvicides are products that kill mosquito larvae. Essential oils and plant extracts are emerging natural sources of larvicides, insecticides and insect antifeedant (Duke, 1990).
Aboaba, S. A., Ibrahum, K., FLAMINI, GUIDO   +2 more
core  

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Essential oils in food preservation, flavor and safety

, 2016
POINTSDISCLAIMER; ACKNOWLEDGMENT; REFERENCES; 3 - Cultivation of Essential Oils; INTRODUCTION; IMPORTANT SPECIES FOR ESSENTIAL OIL CULTIVATION; FACTORS INFLUENCING CULTIVATION OF ESSENTIAL OILS; Environmental Factors; Harvesting-Related Factors ...
Preedy, Victor R.
core  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Thermodynamic parameters for the distillation process in obtaining essential oil from cut fruits [PDF]

BIO Web of Conferences
An experimental steam distillation process was investigated to extract essential oil from cut fruits in a laboratory distillation plant. It was determined that the chemical composition of the obtained primary essential oil. The experiments were performed
Semerdzhieva Ana, Atanasov Dimitar, Atanasova Teodora, Tasheva Stanislava   +3 more
doaj   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source