Results 91 to 100 of about 3,119,098 (305)

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Comparative Study of Antibacterial Activity between Selected International and Indian Essential Oils against Selected Pathogenic Bacteria [PDF]

In recent years, the rapid growth in Antimicrobial resistance (AMR) has become a global concern. Essential oils derived from plants that include bioactive components with proven antioxidative and antibacterial activities could be a potential solution to ...
K.V. Leela, W. Richard Thilagaraj, Pooja Gangadharan, Shweta Sagar Naik   +3 more
core   +1 more source

Validation of a Cellular Imaging‐Based Method as a Potential Biomarker for SPG4 Hereditary Spastic Paraplegia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Hereditary Spastic Paraplegia (HSP) comprises a group of rare genetic diseases characterized by length‐dependent axonal degeneration of the corticospinal tracts and dorsal columns, whose main clinical feature is spastic gait. Pathogenic variants in the SPG4 gene cause Spastic Paraplegia Type 4 (SPG4‐HSP), the most common form of HSP.
Gaia Fattorini, Valerio Licursi, Gianmarco Dalla Zanna, Flavio Dal Canto, Melissa Barghigiani, Nunzio Setola, Salvatore Rossi, Antonio Funcis, Filippo M. Santorelli, Gabriella Silvestri, Carlo Casali, Francesca Sardina, Cinzia Rinaldo   +12 more
wiley   +1 more source

Authenticity assessment of Citrus essential oils

, 2012
Multidimensional Gas Chromatography (MDGC) with a chiral column in the second dimension, and Gas Chromatography Combustion Isotope Ratio Mass Spectrometry (GC-C-IRMS) represent powerful analytical tools for the quality assessment of the genuineness of ...
SCHIPILLITI, LUISA, MONDELLO, Luigi, DUGO, Giovanni, BONACCORSI, Ivana Lidia, SCIARRONE, Danilo   +4 more
core  

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Nematicidal activity of essential oils from Lavandula hybrida

, 2014
Phytoparasitic nematodes can be strongly destructive and extremely difficult to manage due to their poliphagy and worldwide spread. Plant-derived compounds can represent an environmentally sustainable alternative to chemicals for the control of these ...
Sebastiano Laquale, Paola Leonetti, Maria Grazia Bellardi, Trifone D'Addabbo   +3 more
core  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Chemical Composition and Antimicrobial Activity of Essential Oils from Black Pepper, Cumin, Coriander and Cardamom Against Some Pathogenic Microorganisms

Acta Universitatis Cibiniensis. Series E: Food Technology, 2016
Four popular spices black pepper (Piper nigrum L.), cumin (Cuminum cyminum L.), coriander (Coriandrum sativum L.) and cardamom (Elettaria cardamomum) were analyzed for their oil composition by GC-MS.
Teneva Desislava, Denkova Zapryana, Goranov Bogdan, Denkova Rositsa, Kostov Georgi, Atanasova Teodora, Merdzhanov Pavel   +6 more
doaj   +1 more source

Chocolates containing encapsulated in cocoa butter microemulsion cells of a probiotic strain Lactiplantibacillus plantarum [PDF]

BIO Web of Conferences
Chocolates were prepared with the probiotic strain Lactiplantibacillus plantarum 13/20 and a prebiotic component of blackcurrant, cherry and blueberry flours.
Dobrev Iliyan, Goranov Bogdan, Hadjikinova Raina, Denkova Zapryana, Ivanova Petya   +4 more
doaj   +1 more source