Results 1 to 10 of about 3,046,243 (224)

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis [PDF]

Cancer Cell, 2005
Jan Cools, Benjamin L Ebert, Gerlinde Wernig   +2 more
exaly   +3 more sources

Development and validation of a model for the early prediction of progression from essential thrombocythemia to post-essential thrombocythemia myelofibrosis: a multicentre retrospective studyResearch in context [PDF]

EClinicalMedicine
Summary: Background: Essential thrombocythemia (ET), a myeloproliferative neoplasm (MPN), has a substantial risk of evolving into post-essential thrombocythemia myelofibrosis (post-ET MF).
Danhong Xiang, Xiudi Yang, Honglan Qian, Li Zhang, Yanxia Han, Yongcheng Sun, Ying Lu, Yu Chen, Dan Cao, Meiwei Hu, Lifeng Wang, Qinli Tang, Dijiong Wu, Guoyan Tian, Hongyan Tong, Jie Jin, Jian Huang   +16 more
doaj   +2 more sources

Essential thrombocythemia: Rare cause of chorea

Annals of Indian Academy of Neurology, 2014
Essential thrombocythemia (ET) is a clonal myeloproliferative disorder (MPD), characterized predominantly by a markedly elevated platelet count without known cause. It is rare hematological disorder.
Eswaradass Prasanna Venkatesan, Kalidoss Ramadoss, Ramasamy Balakrishnan, B Prakash   +3 more
doaj   +2 more sources

Non-ST-Elevation Myocardial Infarction as the Initial Manifestation of Calreticulin-Positive Essential Thrombocythemia: A Case Report. [PDF]

J Cardiovasc Dev Dis
Hinton JB, Jwayyed JS, Jagetia S, Landwehr HJ, Scrocco JD.   +4 more
europepmc   +3 more sources

Essential Thrombocythemia among Patients with Myeloproliferative Neoplasms in Haematology Unit of a Tertiary Care Centre: A Descriptive Cross-sectional Study

Journal of Nepal Medical Association, 2022
Introduction: Essential thrombocythemia, a myeloproliferative condition with an increased number of circulating platelets, is a rare hematological malignancy. The aim of the study is to find out the prevalence of essential thrombocythemia among patients
Sanjit Kumar Sah, Sangam Shah, Sansar Babu Tiwari, Basanta Sharma Poudel, Biranmol Singh, Prakash Sharma, Sunil Sharma Acharya, Hritik Murarka, Sabin Thapaliya, Anjan Shrestha   +9 more
doaj   +1 more source

Retinal neovascularization in the setting of -mutation positive essential thrombocythemia

SAGE Open Medical Case Reports, 2023
Patients with Calreticulin ( CALR ) mutation positive essential thrombocythemia are often thought of as having a “low-risk” of thrombotic complications.
Stanton P Heydinger, Marwan R Abdulaal, Angeline L Wang   +2 more
doaj   +1 more source

Essential thrombocythemia

Orphanet Journal of Rare Diseases, 2007
Essential thrombocythemia (ET) is an acquired myeloproliferative disorder (MPD) characterized by a sustained elevation of platelet number with a tendency for thrombosis and hemorrhage. The prevalence in the general population is approximately 30/100,000.
Brière Jean B
doaj   +1 more source

Analysis of phenotype and outcome in essential thrombocythemia with CALR or JAK2 mutations

Haematologica, 2015
The JAK2 V617F mutation, the thrombopoietin receptor MPL W515K/L mutation and calreticulin (CALR) mutations are mutually exclusive in essential thrombocythemia and support a novel molecular categorization of essential thrombocythemia.
Carla Al Assaf, Florence Van Obbergh, Johan Billiet, Els Lierman, Timothy Devos, Carlos Graux, Anne-Sophie Hervent, Jan Emmerechts, Thomas Tousseyn, Pascale De Paepe, Petros Papadopoulos, Lucienne Michaux, Peter Vandenberghe   +12 more
doaj   +1 more source

Frequent reduction or absence of detection of the JAK2-mutated clone in JAK2V617F-positive patients within the first years of hydroxyurea therapy

Haematologica, 2008
We analyzed the effect of hydroxyurea on the JAK2V617F allelic ratio (%JAK2V617F), measured in purified blood granulocytes, of patients with polycythemia vera and essential thrombocythemia.
François Girodon, Céline Schaeffer, Cédric Cleyrat, Morgane Mounier, Ingrid Lafont, Frédéric Dos Santos, Aurélie Vidal, Marc Maynadié, Sylvie Hermouet   +8 more
doaj   +1 more source

Isolated ten-eleven translocation 2 positive in triple negative essential thrombocythemia: Case report and literature review

SAGE Open Medical Case Reports, 2021
Essential thrombocythemia is one of the famous diseases under the category of myeloproliferative disorder. It is an end result of a genetic mutation of one or more of the most frequent oncogenes such as Janos kinase 2 (JAK2), MPL proto-oncogene ...
Rehab Y AL-Ansari, Dena Al Otaibi, Nourah Al Hudaithi, Leena Abdalla   +3 more
doaj   +1 more source