Results 31 to 40 of about 3,046,243 (224)

Distinguishing essential thrombocythemia JAK2V617F from polycythemia vera: limitations of erythrocyte values

Haematologica, 2019
Distinguishing essential thrombocythemia JAK2V617F from polycythemia vera is difficult because of shared mutation and phenotypic characteristics. The World Health Organization suggested hemoglobin and hematocrit values to diagnose polycythemia vera (PV),
Richard T. Silver, Spencer Krichevsky
doaj   +1 more source

Recurrent thrombosis of splanchnic and lower extremity arteries with essential thrombocythemia

SAGE Open Medical Case Reports, 2019
Essential thrombocythemia is a myeloproliferative neoplasm characterized by platelet aggregation and thrombosis. Clinically, essential thrombocythemia increases the risk of both thrombosis and bleeding. Essential thrombocythemia is more involved in micro-
Sung Min Jung, Heungman Jun
doaj   +1 more source

Interferon alpha therapy in essential thrombocythemia and polycythemia vera - a systematic review and meta-analysis

Leukemia, 2020
Data on the efficacy and safety of interferon (IFN)-α for the treatment of essential thrombocythemia (ET) and polycythemia vera (PV) are inconsistent.
J. Bewersdorf, S. Giri, Rong Wang, N. Podoltsev, Robert T. Williams, M. Tallman, R. Rampal, A. Zeidan, M. Stahl   +8 more
semanticscholar   +1 more source

Pregnancy with Essential Thrombocythemia: A Case Report

Taiwanese Journal of Obstetrics & Gynecology, 2004
Objective: We describe a woman with essential thrombocythemia (ET) who experienced a successful pregnancy with no specific treatment. Case Report: A 30-year-old primiparous female was incidentally found to have ET with no specific symptoms at a ...
Yin-Jou Chou, Yu-Che Ou, Shiuh-Young Chang, Te-Yao Hsu   +3 more
doaj   +1 more source

Longitudinal Cytokine Profiling Identifies GRO-α and EGF as Potential Biomarkers of Disease Progression in Essential Thrombocythemia

HemaSphere, 2020
Myeloproliferative neoplasms (MPNs) are characterized by deregulation of mature blood cell production and increased risk of myelofibrosis (MF) and leukemic transformation.
N. Øbro, J. Grinfeld, M. Belmonte, Melissa Irvine, Mairi S. Shepherd, T. N. Rao, A. Karow, L. M. Riedel, Oliva B. Harris, E. Baxter, J. Nangalia, A. Godfrey, C. Harrison, Juan Li, R. Skoda, P. Campbell, A. Green, D. Kent   +17 more
semanticscholar   +1 more source

Platelet Toll-Like Receptors Mediate Thromboinflammatory Responses in Patients With Essential Thrombocythemia

Frontiers in Immunology, 2020
Essential thrombocythemia (ET) is comprised among chronic myeloproliferative neoplasms (MPN) and is caused by driver mutations in JAK2, CALR, and MPL, which lead to megakaryocyte proliferation and prominent thrombocytosis.
C. P. Marin Oyarzun, Ana C Glembotsky, N. Goette, P. Lev, Geraldine De Luca, M. C. Baroni Pietto, B. Moiraghi, M. C. Castro Ríos, Á. Vicente, R. Marta, M. Schattner, P. Heller   +11 more
semanticscholar   +1 more source

A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family

Haematologica, 2008
Background Hereditary thrombocythemia is an autosomal dominant disorder with clinical features resembling sporadic essential thrombocythemia.
Kun Liu, Robert Kralovics, Zbigniew Rudzki, Barbara Grabowska, Andreas S. Buser, Damla Olcaydu, Heinz Gisslinger, Ralph Tiedt, Patricia Frank, Krzysztof Okoñ, Anthonie P.C. van der Maas, Radek C. Skoda   +11 more
doaj   +1 more source

A Case of Symptomatic Intraluminal Internal Carotid Artery Thrombus in a Patient with Essential Thrombocythemia Surgically Treated by CEA

Case Reports in Neurological Medicine, 2023
We report a patient with a symptomatic intraluminal internal carotid artery thrombus clinically revealed by cerebral infarction. In the preoperative evaluation, it was revealed that essential thrombocythemia existed in the background.
Satoshi Takahashi, Masahiro Katsumata, Hirotsugu Nogawa, Kento Takahara, Jin Nakahara, Masahiro Toda   +5 more
doaj   +1 more source

Familial Essential Thrombocythemia Associated with MPL W515L Mutation in Father and JAK2 V617F Mutation in Daughter

Case Reports in Hematology, 2014
Familial essential thrombocythemia features the acquisition of somatic mutations and an evolution similar to the sporadic form of the disease. Here we report two patients—father and daughter—with essential thrombocythemia who displayed a heterogeneous ...
Adrian P. Trifa, Andrei Cucuianu, Radu A. Popp   +2 more
doaj   +1 more source

First successful pregnancy outcome after intrauterine insemination in a woman with primary infertility and essential thrombocythemia treated with interferon-alpha and aspirin [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2015
Introduction. The management of pregnancy in young women with essential thrombocythemia is complex and may present a difficult problem. An adverse pregnancy outcome due to thrombosis or bleeding is a common complication.
Leković Danijela, Gotić Mirjana, Ljubić Aleksandar   +2 more
doaj   +1 more source