Results 11 to 20 of about 8,451 (175)

Essential tremor-plus: a controversial new concept. [PDF]

Lancet Neurol, 2020
In addition to redefining essential tremor (ET), the 2018 consensus statement of the Movement Disorder Society on tremor coined a new term: essential tremor-plus (ET-plus). This term is uncertainly defined as tremor with the characteristics of ET, with additional neurological signs of uncertain clinical significance.
Louis ED, Bares M, Benito-Leon J, Fahn S, Frucht SJ, Frucht SJ, Jankovic J, Ondo WG, Pal PK, Tan EK.   +9 more
europepmc   +3 more sources

A Novel KCNN2 Variant in a Family with Essential Tremor Plus: Clinical Characteristics and In Silico Analysis. [PDF]

Genes (Basel), 2023
Background: Essential tremor (ET) is one of the more common movement disorders. Current diagnosis is solely based on clinical findings. ET appears to be inherited in an autosomal dominant pattern. Several loci on specific chromosomes have been studied by linkage analysis, but the causes of essential tremor are still unknown in many patients.
d'Apolito M, Ceccarini C, Savino R, Adipietro I, di Bari I, Santacroce R, Curcetti M, D'Andrea G, Croce AI, Cesarano C, Polito AN, Margaglione M.   +11 more
europepmc   +4 more sources

[Essential tremor: are we just splitting hairs? Non-motor symptoms and essential tremor-plus]. [PDF]

Rev Neurol, 2023
The existence of non-motor symptoms in essential tremor (ET) and the appearance of a new condition, ET-plus, are two controversial issues.To offer a review of the current status of these two topics.We performed an analysis of the studies conducted on non-motor symptoms in ET and of the articles for and against the use of the term ET-plus.Non-motor ...
Gironell A.
europepmc   +3 more sources

The Problem of Questionable Dystonia in the Diagnosis of 'Essential Tremor-Plus'. [PDF]

Tremor Other Hyperkinet Mov (N Y), 2020
In a recent consensus statement on tremor, the task force of the International Parkinson and Movement Disorder Society proposed a new term, 'essential tremor-plus (ET-plus)' which includes patients with the characteristics of essential tremor (ET) and additional soft neurological signs of uncertain significance such as questionable dystonic posturing ...
Pandey S, Bhattad S, Hallett M.
europepmc   +4 more sources

“ET Plus”: Instability of the Diagnosis During Prospective Longitudinal Follow-up of Essential Tremor Cases [PDF]

Frontiers in Neurology, 2021
Background: A recent consensus statement introduced the term “ET plus”. Although investigators have quantified the prevalence of ET plus in cross-sectional studies, patients with ET plus have not been tracked longitudinally; hence, there is no ...
Daniella Iglesias-Hernandez, Nikki Delgado, Margaret McGurn, Edward D. Huey, Edward D. Huey, Edward D. Huey, Stephanie Cosentino, Stephanie Cosentino, Elan D. Louis   +8 more
doaj   +3 more sources

Striatal Dopaminergic Function and Motor Slowing in Essential Tremor Plus. [PDF]

Mov Disord Clin Pract
AbstractBackgroundWhile previous imaging studies have generally shown normal striatal dopamine transporter (DAT) binding in essential tremor (ET), emerging evidence suggests a partial dopaminergic mechanism in this condition and an epidemiological link between ET and Parkinson's disease (PD).
Kuusela AM, Honkanen EA, Jaakkola E, Myller E, Eklund M, Nuuttila S, Murtomäki KM, Mertsalmi T, Levo R, Ihalainen T, Noponen T, Vahlberg T, Joutsa J, Scheperjans F, Kaasinen V.   +14 more
europepmc   +4 more sources

Polysomnographic Evaluation of Sleep Disorders in Essential Tremor and Essential Tremor Plus: A Comparison With Healthy Controls. [PDF]

J Mov Disord
Objective To explore sleep patterns in individuals with essential tremor (ET) and essential tremor plus (ET-Plus) compared with healthy controls and assess differences between ET and ET-Plus, given the lack of established polysomnography (PSG) data on these groups and the potential for sleep disturbances to serve as clinical markers.Methods We ...
Singh RP, S M, Seshagiri DV, Kumar G, Mohale R, Pal PK, Kutty BM, Saini J, Kamble NL, Holla V, Yadav R.   +10 more
europepmc   +3 more sources

Questionable Dystonia in Essential Tremor Plus: A Video-Based Assessment of 19 Patients. [PDF]

Mov Disord Clin Pract, 2019
View Supplementary Video ...
Pandey S, Bhattad S.
europepmc   +4 more sources

Tremor: Clinical Frameworks, Network Dysfunction and Therapeutics [PDF]

Brain Sciences
Background: Tremor is a common but diagnostically challenging movement disorder due to its clinical heterogeneity and overlapping aetiologies.
Emmanuel Ortega-Robles, Oscar Arias-Carrión   +1 more
doaj   +2 more sources

Quercetin nanoemulsion ameliorates tremor and neuroinflammatory dysregulation: behavioral and molecular insights in a mouse model of essential tremor [PDF]

Behavioral and Brain Functions
Background Essential tremor (ET) is a common movement disorder characterized by persistent limb tremors. Currently, no effective treatment for ET exists.
Zeynab Pirmoradi, Monavareh Soti, Kristi A. Kohlmeier, Mohammad Shabani, Fatemeh Shahsavari   +4 more
doaj   +2 more sources