Results 81 to 90 of about 8,451 (175)

Rationale and design of a parallel randomised trial of a plant‐based intensive lifestyle intervention for diabetes remission: The REmission of diabetes using a PlAnt‐based weight loss InteRvention (REPAIR) trial

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2627-2641, April 2026.
Abstract Aims As type 2 diabetes (T2D) continues to rise globally and remains a major driver of cardiovascular disease, its remission has emerged as a therapeutic target. Current evidence supports bariatric surgery and low‐calorie diets with meal replacements.
Brighid McKay, Dayana El Chaar, Melanie Paquette, Michael Vallis, Diana Sherifali, Paul Oh, Susan Marzolini, Kaberi Dasgupta, Gillian Booth, Mike Lean, Hertzel C. Gerstein, Jordi Salas‐Salvadó, Jacqueline L. Beaudry, Christopher P. F. Marinangeli, Russell J. de Souza, Lawrence A. Leiter, Cyril W. C. Kendall, David J. A. Jenkins, John L. Sievenpiper, Laura Chiavaroli   +19 more
wiley   +1 more source

Photon‐Counting CT for Diagnosing Vertical Root Fractures in Teeth With Metal Posts: An Ex Vivo Comparative Analysis With Four CBCT Devices

International Endodontic Journal, Volume 59, Issue 4, Page 718-727, April 2026.
ABSTRACT Objective Photon‐counting computed tomography (PCCT) represents a major innovation in X‐ray detection technology, offering improved signal efficiency and reduced electronic noise compared with cone‐beam computed tomography (CBCT), which can enhance image quality.
Renata M. S. Leal, Fernanda B. Fagundes, Maria F. S. A. Bortoletto, Samuel C. Kluthcovsky, Walter Coudyzer, Bruno C. Cavenago, Reinhilde Jacobs, Rocharles Cavalcante Fontenele   +7 more
wiley   +1 more source

General practice veterinarians’ attitudes towards avian influenza: A COM‐B analysis of barriers to backyard poultry treatment

Veterinary Record, Volume 198, Issue 6, Page e237-e247, 14/21 March 2026.
Abstract Background The recent expansion of highly pathogenic avian influenza (HPAI) H5N1 to non‐avian species in the United States has intensified public health‐related concerns. In Great Britain, low veterinarian confidence in seeing and treating birds creates potential barriers to HPAI diagnosis and reporting.
Sol Elliott, Sarah Jewitt, Emma McClaughlin, Matthew Smallman‐Raynor, Sioux Fisher, Michael Clark, Rachael Tarlinton   +6 more
wiley   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, Volume 13, Issue 13, 3 March 2026.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

Wearable Metamaterials with Embodied Intelligence for Programmable Control of Human Limbs Tremor

Advanced Intelligent Systems, Volume 8, Issue 3, March 2026.
Resulting from alternating muscle contractions, tremors can severely limit human ability to perform everyday tasks like walking or talking, due to their disruptive nature. Medication and surgery may not always effectively address tremor control. A wearable device embodying programmable smart metamaterials with adaptable intelligence to meet the demand ...
Braion Barbosa de Moura, Marcela R. Machado, Tanmoy Mukhopadhyay   +2 more
wiley   +1 more source

Effectiveness, safety, and biomarker dynamics of lecanemab in Chinese Alzheimer's disease population: a multicenter real‐world study

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
ABSTRACT BACKGROUND Lecanemab, an anti–amyloid beta (Aβ) protofibril antibody, was introduced in China in 2024, but its real‐world performance remains unknown. METHODS In this prospective, multicenter study across 21 sites, 261 Alzheimer's disease patients (mild cognitive impairment to moderate dementia) received biweekly lecanemab (10 mg/kg).
Wang Liao, Qun Yu, Bin Chen, Hualin Chen, Liangyu Zou, Haiqun Xie, Haobo Chen, Chenyang Wang, Yang Li, Xiaoya Gao, Hongbo Guo, Ying Yang, Ziyu She, Qinggan Zeng, Zengqiang Zhang, Guihua Li, Shujun Feng, Han Lin, Jipeng Ouyang, Junyan Liang, Wenling Ao, Qiong Zeng, Zhou Liu, Hanyu Weng, Hongqiang Huang, Feiqi Zhu, Runni Liu, Yingte Wang, Dapeng Yu, Xue Li, Yingren Mai, Shengnan Jiang, Yu Tu, Zhiming Li, Jun Liu, for the Alzheimer's Disease Neuroimaging Initiative   +35 more
wiley   +1 more source

Effects of Tetrodotoxin on Safety, and Sensory and Respiratory Systems: A Dose‐Escalating Study in Healthy Volunteers

European Journal of Pain, Volume 30, Issue 3, March 2026.
ABSTRACT Background Chronic pain affects approximately 1.5 billion individuals worldwide, and currently available treatments often fail to provide adequate analgesia. Consequently, there is a need to explore novel analgesic compounds, including tetrodotoxin.
Kiki W. K. Kuijpers, Rutger Van Der Schrier, Albert Dahan, Monique Van Velzen   +3 more
wiley   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, Volume 12, Issue 1, Page 3-37, Spring 2026.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Nebulized Lidocaine Through a Channeled Endoscope for Office Laryngology Procedures

The Laryngoscope, Volume 136, Issue 3, Page 1409-1415, March 2026.
Targeted delivery of nebulized lidocaine through a channeled endoscope may improve patient tolerance and reduce lidocaine dosage for office laryngology procedures. Most patients in this study preferred channel‐nebulized lidocaine over trans‐tracheal and laryngeal drip topical lidocaine.
Dylan Z. Erwin, Abigail N. Kennedy, Matthew Y. Liu, Laura M. Dominguez, C. Blake Simpson, Zao Mike Yang   +5 more
wiley   +1 more source

AI‐Driven Revolution of Medical Robotics Across Surgical Innovation, Rehabilitation Intelligence, and Multimodal Healthcare Delivery

MedComm, Volume 7, Issue 3, March 2026.
The figure illustrates the background, applications, limitations, and future trends of medical robotics in the context of global aging and strained medical resources. It highlights issues such as the increasing demand for healthcare due to aging populations, with a focus on applications in surgery, rehabilitation, medical examination, and assistance ...
Fanxuan Chen, Haoman Chen, Tao Yu, Ruoyun Wang, Yi Wang, Xian Zhang, Jiachen Li, Kaishuo Liu, Darong Hai, Xueying Bao, Zefei Mo, Dongren Yang, Zhao Wang, Youhui Lin, Qinghua Xia, Gen Yang, Jianwei Shuai   +16 more
wiley   +1 more source