Results 31 to 40 of about 58,657 (212)
Law, Ethics and Philosophy, 2015 According to the Internal Aspects View, the value of different outcomes depends solely on the internal features possessed by each outcome and the internal relations between them. This paper defends the Internal Aspects View against Larry Temkin’s defence
Oscar Horta
doaj
Teori Gradasi : Komparasi Antara Ibn Sina, Suhrawardi Dan Mulla Sadra
Kanz Philosophia: A Journal for Islamic Philosophy and Mysticism, 2015 Prior to Mullā Ṣadrā, the discussion of the gradation (al-tashkīk) was limited on the category of quality and that of quantity, both are known as the differential gradation (al-tashkīk al- tafāḍulī).
Benny Susilo
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Rethinking the Good – A Small Taste
Law, Ethics and Philosophy, 2015 This article aims to convey a few of the key claims and arguments of my book, Rethinking the Good: Moral Ideals and the Nature of Practical Reasoning. The article gives an example of a Spectrum Argument, and illustrates that such arguments put pressure ...
Larry Temkin
doaj
Oriental Studies, 2018 The paper presents analysis of a new kind of educational courses based on multidisciplinary approach. The course synthesizes the methodologies and advances of regional studies and regional geography, cultural and cross-cultural studies and communication,
A. Stepanova
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Law, Ethics and Philosophy, 2015 This article responds to Oscar Horta’s article “In Defense of the Internal Aspects View: Person-Affecting Reasons, Spectrum Arguments and Inconsistent Intuitions”. I begin by noting various points of agreement with Horta.
Larry Temkin
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
PHILOSOPHY OF INFORMATION AND TRANSHUMANISM: EXPLICATIONS OF PHILOSOPHICAL ANTHROPOLOGY
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2019 Purpose. The research is aimed at finding out the grounds, forms and essence of the correlation between the projects of information philosophy and transhumanism from the point of view of the problematics of philosophical anthropology.
O. V. Marchenko, P. V. Kretov
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source