Results 41 to 50 of about 58,657 (212)

Internal or External Grounds for the Nontransitivity of “Better/Worse than”

open access: yesLaw, Ethics and Philosophy, 2015
In his book Rethinking the Good: Moral Ideals and the Nature of Practical Reasoning Larry Temkin contrasts two views of ideals for evaluating outcomes: the Internal Aspects View and the Essentially Comparative View.
Ingmar Persson
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

About riders as employees

open access: yesLabour & Law Issues, 2019
In reminding us of the need for a careful analysis of the different forms in which work using digital platforms can be presented in the present world, in this work the author shows that, although in doctrine we have spoken of "qualifying obsession", the ...
Marco Barbieri
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Tentative estimation of possibilities of use of polymeric composite materials for increase of reliability of storage and the burial place of the radioactive waste

open access: yesRUDN Journal of Ecology and Life Safety, 2009
In article are considered fisic-mechanical properties of a composite material «Sintegran», their comparative analysis with the traditional materials used in mechanical engineering and other branches of a national economy is given.
V N Barinov   +4 more
doaj  

The YMCA in Central European Countries as One of the Ways of Americanising Central Europe after the First World War (Base of Information and Methodological Approaches zo Researching the Issue)

open access: yesActa Universitatis Carolinae Kinanthropologica, 2014
The YMCA in Central European Countries as One of the Ways of Americanising Central Europe after the First World War (Base of Information and Methodological Approaches zo Researching the Issue) The YMCA is essentially an organisation uniting people of ...
Tomáš Tlustý
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reflexive Methods of Knowledge in Educational Activities: Phenomenological Hermeneutics

open access: yesОбразование и наука, 2019
Introduction. Knowledge is one of the most important human needs. Today, lifelong learning and self-education individual skills are of paramount importance for each representative of the society in relation to the world trends of a post-industrial era ...
T. N. Korneenko
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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