Results 51 to 60 of about 18,160,584 (274)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Internal or External Grounds for the Nontransitivity of “Better/Worse than”
Law, Ethics and Philosophy, 2015 In his book Rethinking the Good: Moral Ideals and the Nature of Practical Reasoning Larry Temkin contrasts two views of ideals for evaluating outcomes: the Internal Aspects View and the Essentially Comparative View.
Ingmar Persson
doaj
Oriental Studies, 2018 The paper presents analysis of a new kind of educational courses based on multidisciplinary approach. The course synthesizes the methodologies and advances of regional studies and regional geography, cultural and cross-cultural studies and communication,
A. Stepanova
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
PHILOSOPHY OF INFORMATION AND TRANSHUMANISM: EXPLICATIONS OF PHILOSOPHICAL ANTHROPOLOGY
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2019 Purpose. The research is aimed at finding out the grounds, forms and essence of the correlation between the projects of information philosophy and transhumanism from the point of view of the problematics of philosophical anthropology.
O. V. Marchenko, P. V. Kretov
doaj +1 more source
Comparative Literature in Canada: A Case Study [PDF]
, 2013 On the history of the Comparative Literature program at the University of ...
Blodgett, E.D.
core
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
RUDN Journal of Ecology and Life Safety, 2009 In article are considered fisic-mechanical properties of a composite material «Sintegran», their comparative analysis with the traditional materials used in mechanical engineering and other branches of a national economy is given.
V N Barinov +4 more
doaj
Labour & Law Issues, 2019 In reminding us of the need for a careful analysis of the different forms in which work using digital platforms can be presented in the present world, in this work the author shows that, although in doctrine we have spoken of "qualifying obsession", the ...
Marco Barbieri
doaj +1 more source
On the State of Comparative Literature in Canada [PDF]
, 2014 "The way Comparative Literature has been bloated during the last few decades in order to cope with the threat of being usurped by some of the newborn disciplines is not only surprising but also what fundamentally defines Comparative Literature today ...
Ray, Avishek
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